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Summary Expression Phenotypes Gene Literature (16) GO Terms (11) Nucleotides (137) Proteins (37) Interactants (208) Wiki
XB-GENEPAGE-478671
Gene Symbol:
 irs1

Gene Name: 
insulin receptor substrate 1

Synonyms:
irs-1 , LOC108718134 ( Nomenclature history )

Gene Function:
exo-a-sialidase

Protein Function :
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidyl...[+]


InterPro :
IRS PTB, PH domain, PH-like dom sf, IRS

Interactants:
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Diseases: 


Disease Ontology:
type 2 diabetes mellitus

MIM:
TYPE 2 DIABETES MELLITUS; T2D

External Links:
 
Expression                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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