Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also inter...[+]

Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. [-]

             restrictive dermopathy
             Charcot-Marie-Tooth disease type 2B1
             autosomal dominant limb-girdle muscular dystrophy type 1B
             dilated cardiomyopathy 1A
             congenital muscular dystrophy due to LMNA mutation
             Emery-Dreifuss muscular dystrophy
             progeria
             Werner syndrome
             dilated cardiomyopathy-hypergonadotropic hypogonadism syndrome
             familial partial lipodystrophy type 2
             mandibuloacral dysplasia type A lipodystrophy
             restrictive dermopathy 1
             autosomal recessive Emery-Dreifuss muscular dystrophy 3
             autosomal dominant Emery-Dreifuss muscular dystrophy 2

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD