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Summary Expression Phenotypes Gene Literature (19) GO Terms (13) Nucleotides (125) Proteins (65) Interactants (163) Wiki
XB-GENEPAGE-479045
Gene Symbol:
 smurf1

Gene Name: 
SMAD specific E3 ubiquitin protein ligase 1

Synonyms:
xSMURF1 ( Nomenclature history )

Gene Function:
ubiquitin protein ligase

Protein Function :
E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of smad1 and smad5, 2 receptor-regulated SMADs specific for the BMP pathw...[+]


InterPro :
C2 dom, C2 domain sf, E3 ub ligase SMURF1, E3 ubiq-protein ligase, [+]

Interactants:
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Diseases: 


External Links:
 
Expression                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info