The s100a11 gene encodes a calcium-binding protein of the S100 family expressed during embryonic development, particularly within the epidermis, skin, cornea, and cement gland. The protein is localized...[+]

The s100a11 gene encodes a calcium-binding protein of the S100 family expressed during embryonic development, particularly within the epidermis, skin, cornea, and cement gland. The protein is localized to the cytosol and can translocate to the plasma membrane and nucleus in a calcium-dependent manner. It functions in intracellular signaling, epidermal differentiation, and keratinocyte development. This protein interacts with other proteins such as annexins to regulate processes like cell cycle progression and cytoskeletal dynamics. [-]

ClinVar, ClinGen, MalaCards, KEGG Disease, DECIPHER, COSMIC, MARRVEL, GTR, DisGeNET, dbVAR, GHR, gnomAD