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Summary Expression Phenotypes Gene Literature (21) GO Terms (182) Nucleotides (186) Proteins (57) Interactants (703) Wiki
XB-GENEPAGE-480854
Gene Symbol:
 apc

Gene Name: 
APC regulator of Wnt signaling pathway

Synonyms:
adenomatosis polyposis coli , xapc ( Nomenclature history )

Gene Function:
tumor suppressor

AI Protein Function :
The apc protein functions as a negative regulator of the Wnt signaling pathway, acting as a scaffold protein in the destruction complex that targets β-catenin for degradation. It localizes to the nucle...[+]


InterPro :
Armadillo, APC N, Apc fam, APC 15aa rpt, [+]

Interactants:
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Diseases: 


Disease Ontology:
familial adenomatous polyposis [+]

MIM:
MEDULLOBLASTOMA; MDB [+]

External Links:
1/4
 
Expression                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


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