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Summary Expression Phenotypes Gene Literature (13) GO Terms (3) Nucleotides (228) Proteins (43) Interactants (258) Wiki
XB-GENEPAGE-954260
Gene Symbol:
 ldlrap1

Gene Name: 
low density lipoprotein receptor adaptor protein 1

Synonyms:
arh , arh1 , fhcb1 , fhcb2 , ldlrap1-a , ldlrap1-b [+] ( Nomenclature history )

Gene Function:
Adaptor protein CED-6, contains PTB domain

Protein Function :
Adapter protein (clathrin-associated sorting protein (CLASP)) required for efficient endocytosis of the LDL receptor (LDLR). Also involved in the vitellogenin receptor mediated endocytosis of nutrients...[+]


InterPro :
PH-like dom sf, PTB/PI dom, Adapter Engulfment-Domain

Interactants:
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Diseases: 


Disease Ontology:
autosomal recessive hypercholesterolemia

MIM:
HYPERCHOLESTEROLEMIA, FAMILIAL, 4; FHCL4

External Links:
 
Expression                  Development Stages                                               Embryonic Tissues                                                                Adult Tissues
More Information
Xenbase Expression Details In situ images Single cell data at SPRING In situ: RNA-Seq:


Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info