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Summary Expression Phenotypes Gene Literature (2) GO Terms (17) Nucleotides (258) Proteins (56) Interactants (90) Wiki
XB-GENEPAGE-1006691

Show:     All X. tropicalis X. laevis

Nucleotide sequences for aldh6a1 - All

RefSeq mRNAs(5)
Models - Gene (29)
Models - mRNA (38)
mRNAs (9)
ESTs (141)

RefSeq mRNAs (5)

Accession Version Protein Name Length Protein Species
XM_002938588 XM_002938588.5 methylmalonate-semialdehyde dehydrogenase 2450 bp XP_002938634 X. tropicalis
NM_001096420 NM_001096420.1 aldehyde dehydrogenase 6 family member A1 L homeolog 2384 bp NP_001089889 X. laevis.L
XM_018232458 XM_018232458.2 methylmalonate-semialdehyde dehydrogenase 2203 bp XP_018087947 X. laevis.S
XM_018232459 XM_018232459.1 methylmalonate-semialdehyde dehydrogenase 2076 bp XP_018087948 X. laevis.S
XM_041574939 XM_041574939.1 XP_041430873.1 methylmalonate-semialdehyde dehydrogenase 2118 bp XP_041430873 X. laevis.S

Models - Gene (29)

Source Version Model Species
NCBI 10.1 XBXL10_1g37418 X. laevis.S
NCBI 10.1 XBXL10_1g35694 X. laevis.L
NCBI 10.0 XBXT10g019747 X. tropicalis
ENSEMBL 10.0 ENSXETG00000013304 X. tropicalis
Xenbase 9.2 gene7153 X. laevis.L
Xenbase 9.2 gene5375 X. laevis.S
JGI 9.1 Xelaev18039438m.g X. laevis.L
JGI 9.1 Xelaev18041381m.g X. laevis.S
Xenbase 9.1 gene18135 X. tropicalis
ENSEMBL 9.1 ENSXETG00000013304 X. tropicalis
JGI 8.0 Xetrov14034362m.g X. tropicalis
JGI 7.2 Xelaev16050773m.g X. laevis.L
JGI 7.1 Xetro.H01146 X. tropicalis
JGI 6.0 XeXenL6RMv10020102m.g X. laevis.L
ENSEMBL 4.1 ENSXETG00000013304 X. tropicalis
JGI 4.1 fgenesh1_pg.C_scaffold_389000032 X. tropicalis
JGI 4.1 fgenesh1_kg.C_scaffold_389000011 X. tropicalis
JGI 4.1 estExt_fgenesh1_kg.C_3890011 X. tropicalis
JGI 4.1 estExt_Genewise1.C_3890107 X. tropicalis
JGI 4.1 estExt_Genewise1.C_3890049 X. tropicalis
JGI 4.1 estExt_Genewise1.C_3890004 X. tropicalis
JGI 4.1 estExt_FilteredModels1.C_3890021 X. tropicalis
JGI 4.1 gw1.389.51.1 X. tropicalis
JGI 4.1 gw1.389.4.1 X. tropicalis
JGI 4.1 gw1.389.110.1 X. tropicalis
JGI 4.1 e_gw1.389.51.1 X. tropicalis
JGI 4.1 e_gw1.389.4.1 X. tropicalis
JGI 4.1 e_gw1.389.110.1 X. tropicalis
JGI 4.1 estExt_fgenesh1_pg.C_3890030 X. tropicalis

mRNAs based on gene models(38)

Source Version Model Species
NCBI 10.1 XBmRNA70625 X. laevis.S
NCBI 10.1 XBmRNA67379 X. laevis.L
NCBI 10.0 mRNA097473 X. tropicalis
ENSEMBL 10.0 ENSXETT00000029150 X. tropicalis
ENSEMBL 10.0 ENSXETT00000069090 X. tropicalis
ENSEMBL 10.0 ENSXETT00000075659 X. tropicalis
ENSEMBL 10.0 ENSXETT00000100991 X. tropicalis
Xenbase 9.2 rna20877 X. laevis.L
Xenbase 9.2 rna15761 X. laevis.S
Xenbase 9.1 rna38714 X. tropicalis
JGI 9.1 Xelaev18041381m X. laevis.S
JGI 9.1 Xelaev18039438m X. laevis.L
ENSEMBL 9.1 ENSXETT00000100991 X. tropicalis
ENSEMBL 9.1 ENSXETT00000094736 X. tropicalis
ENSEMBL 9.1 ENSXETT00000076505 X. tropicalis
ENSEMBL 9.1 ENSXETT00000075659 X. tropicalis
ENSEMBL 9.1 ENSXETT00000069090 X. tropicalis
ENSEMBL 9.1 ENSXETT00000029150 X. tropicalis
JGI 8.0 Xetrov14034362m X. tropicalis
JGI 7.2 Xelaev16050773m X. laevis.L
JGI 7.1 Xetro.H01146.1 X. tropicalis
JGI 7.1 Xetro.H01146.2 X. tropicalis
JGI 6.0 XeXenL6RMv10020102m X. laevis.L
JGI 4.1 gw1.389.4.1 X. tropicalis
JGI 4.1 gw1.389.51.1 X. tropicalis
JGI 4.1 fgenesh1_kg.C_scaffold_389000011 X. tropicalis
JGI 4.1 estExt_Genewise1.C_3890107 X. tropicalis
JGI 4.1 estExt_Genewise1.C_3890049 X. tropicalis
JGI 4.1 estExt_Genewise1.C_3890004 X. tropicalis
JGI 4.1 estExt_FilteredModels1.C_3890021 X. tropicalis
JGI 4.1 estExt_fgenesh1_pg.C_3890030 X. tropicalis
JGI 4.1 estExt_fgenesh1_kg.C_3890011 X. tropicalis
JGI 4.1 e_gw1.389.4.1 X. tropicalis
JGI 4.1 e_gw1.389.51.1 X. tropicalis
JGI 4.1 e_gw1.389.110.1 X. tropicalis
ENSEMBL 4.1 ENSXETT00000029150 X. tropicalis
JGI 4.1 fgenesh1_pg.C_scaffold_389000032 X. tropicalis
JGI 4.1 gw1.389.110.1 X. tropicalis

mRNAs from cDNA libraries (9)

Clone Accession Species Library Anatomy Stage
XM_002938588 X. tropicalis
AY851298 X. laevis.L
IMAGE:7210478 BC108615 X. laevis.L
NM_001096420 X. laevis.L
IMAGE:6867078 BC100237 X. laevis.S Wellcome CRC pSK egg egg unfertilized egg stage
IMAGE:6861012 BC126042 X. laevis.S
XM_018232458 X. laevis.S
XM_018232459 X. laevis.S
XM_041574939 X. laevis.S

ESTs (141)

Clone Accession 5'/3' Species Library Anatomy Stage
IMAGE:6984183 CF152164 5' X. tropicalis NICHD_XGC_Emb8 whole organism NF stage 40 to NF stage 45
IMAGE:8865751 EL703122 5' X. tropicalis NICHD_XGC_tropLimb_m limb NF stage 55 to NF stage 66
IMAGE:8869089 EL709105 5' X. tropicalis NICHD_XGC_tropLimb_m limb NF stage 55 to NF stage 66
IMAGE:8906548 EL799143 5' X. tropicalis NICHD_XGC_tropTail_m tail NF stage 55 to NF stage 66
IMAGE:8959770 EL654677 5' X. tropicalis NICHD_XGC_tropInt_63 intestine unspecified stage
IMAGE:8962859 EL659756 5' X. tropicalis NICHD_XGC_tropInt_66 intestine unspecified stage
IMAGE:8958861 EL663028 5' X. tropicalis NICHD_XGC_tropInt_63 intestine unspecified stage
IMAGE:7030137 CF782388 5' X. tropicalis XtSt10-30 whole organism NF stage 10 to NF stage 29 and 30
TGas009b03 AL630249 5' X. tropicalis XGC-gastrula whole organism NF stage 10.5 to NF stage 12
TGas067f09 AL681464 5' X. tropicalis XGC-gastrula whole organism NF stage 10.5 to NF stage 12
IMAGE:7570343 CX454547 5' X. tropicalis NIH_XGC_tropGas7 whole organism NF stage 10.5 to NF stage 12.5
IMAGE:7568861 CX456645 5' X. tropicalis NIH_XGC_tropGas7 whole organism NF stage 10.5 to NF stage 12.5
IMAGE:7545850 CX488441 5' X. tropicalis NIH_XGC_tropGas7 whole organism NF stage 10.5 to NF stage 12.5
TNeu055j13 AL676906 5' X. tropicalis XGC-neurula whole organism NF stage 13 to NF stage 21
TNeu089e20 AL785223 5' X. tropicalis XGC-neurula whole organism NF stage 13 to NF stage 21
IMAGE:7516447 CX747347 5' X. tropicalis NIH_XGC_tropNeu5 whole organism NF stage 14 to NF stage 18
TTbA005g04 CR414542 5' X. tropicalis XGC-tailbud whole organism NF stage 28 to NF stage 29 and 30
TTbA006k08 CR416800 5' X. tropicalis XGC-tailbud whole organism NF stage 28 to NF stage 29 and 30
TTbA037g11 CR418598 5' X. tropicalis XGC-tailbud whole organism NF stage 28 to NF stage 29 and 30
TTbA039o06 CR439342 5' X. tropicalis XGC-tailbud whole organism NF stage 28 to NF stage 29 and 30
TTbA011m02 CR448237 5' X. tropicalis XGC-tailbud whole organism NF stage 28 to NF stage 29 and 30
THdA024o22 CR571197 5' X. tropicalis XGC-tailbud-head head NF stage 28 to NF stage 29 and 30
THdA018p22 CR581947 5' X. tropicalis XGC-tailbud-head head NF stage 28 to NF stage 29 and 30
TTpA022l05 BX702913 5' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
TTpA005m01 BX706507 5' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
TTpA024c19 BX709803 5' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
TTpA015l20 BX714680 5' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
TTpA063k03 BX716456 5' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
TTpA063b03 BX718979 5' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
TTpA037f09 BX720080 5' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
TTpA068p05 BX721626 5' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
TTpA068p09 BX721629 5' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
TTpA054e13 BX725994 5' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
TTpA049k18 BX727926 5' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
TTpA071e08 BX728196 5' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
TTpA056b09 BX729578 5' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
IMAGE:7784924 CX315787 5' X. tropicalis NIH_XGC_tropTad5 whole organism NF stage 35 and 36 to NF stage 41
IMAGE:7596103 CX336126 5' X. tropicalis NIH_XGC_tropTad5 whole organism NF stage 35 and 36 to NF stage 41
IMAGE:7635921 CX339698 5' X. tropicalis NIH_XGC_tropTad5 whole organism NF stage 35 and 36 to NF stage 41
IMAGE:7618526 CX345919 5' X. tropicalis NIH_XGC_tropTad5 whole organism NF stage 35 and 36 to NF stage 41
IMAGE:7632219 CX397585 5' X. tropicalis NIH_XGC_tropTad5 whole organism NF stage 35 and 36 to NF stage 41
XZT4019 CX399759 5' X. tropicalis NIH_XGC_tropTad5 whole organism NF stage 35 and 36 to NF stage 41
IMAGE:7627652 DR900353 5' X. tropicalis NIH_XGC_tropTad5 whole organism NF stage 35 and 36 to NF stage 41
IMAGE:7790967 DR905689 5' X. tropicalis NIH_XGC_tropTad5 whole organism NF stage 35 and 36 to NF stage 41
IMAGE:5381338 BQ526902 5' X. tropicalis NICHD_XGC_Emb8 whole organism NF stage 40 to NF stage 45
IMAGE:6984247 CF151817 5' X. tropicalis NICHD_XGC_Emb8 whole organism NF stage 40 to NF stage 45
xtbs16F01 CN079455 5' X. tropicalis Xenopus tropicalis xtbs plasmid library central nervous system NF stage 58 to NF stage 64
xtbs30K19 CN088485 5' X. tropicalis Xenopus tropicalis xtbs plasmid library central nervous system NF stage 58 to NF stage 64
IMAGE:7017136 CF524975 5' X. tropicalis NICHD_XGC_Swb1 whole organism frog
IMAGE:7650648 CX811667 5' X. tropicalis NIH_XGC_tropBrn2 brain frog
IMAGE:7665540 CX850869 5' X. tropicalis NIH_XGC_tropBrn4 brain frog
CAAN11075 CX926605 5' X. tropicalis NIH_XGC_tropTe4 testis frog
IMAGE:7698211 CX929896 5' X. tropicalis NIH_XGC_tropTe5 testis frog
IMAGE:7717977 CX979967 5' X. tropicalis NIH_XGC_tropInt1 intestine frog
IMAGE:7733974 DN018570 5' X. tropicalis NIH_XGC_tropLiv1 liver frog
IMAGE:7747123 DN042902 5' X. tropicalis NIH_XGC_tropKid1 mesonephric kidney frog
IMAGE:7753512 DN054791 5' X. tropicalis NIH_XGC_tropKid1 mesonephric kidney frog
IMAGE:8917097 EL830258 5' X. tropicalis NICHD_XGC_tropTe1 testis frog
IMAGE:8921273 EL835471 5' X. tropicalis NICHD_XGC_tropTe1 testis frog
IMAGE:8885863 EL842763 5' X. tropicalis NICHD_XGC_trop_25 whole organism NF stage 25
IMAGE:8892079 EL852215 5' X. tropicalis NICHD_XGC_trop_25 whole organism NF stage 25
TTbA005g04 CR414543 3' X. tropicalis XGC-tailbud whole organism NF stage 28 to NF stage 29 and 30
IMAGE:7733974 DN018569 3' X. tropicalis NIH_XGC_tropLiv1 liver frog
TTbA039o06 CR439343 3' X. tropicalis XGC-tailbud whole organism NF stage 28 to NF stage 29 and 30
IMAGE:8917097 EL830259 3' X. tropicalis NICHD_XGC_tropTe1 testis frog
xtbs16F01 CN079454 3' X. tropicalis Xenopus tropicalis xtbs plasmid library central nervous system NF stage 58 to NF stage 64
IMAGE:7717977 CX979966 3' X. tropicalis NIH_XGC_tropInt1 intestine frog
TGas067f09 BX748872 3' X. tropicalis XGC-gastrula whole organism NF stage 10.5 to NF stage 12
IMAGE:7570343 CX454546 3' X. tropicalis NIH_XGC_tropGas7 whole organism NF stage 10.5 to NF stage 12.5
TTpA071e08 BX728197 3' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
IMAGE:7568861 CX456644 3' X. tropicalis NIH_XGC_tropGas7 whole organism NF stage 10.5 to NF stage 12.5
xtbs30K19 CN088484 3' X. tropicalis Xenopus tropicalis xtbs plasmid library central nervous system NF stage 58 to NF stage 64
IMAGE:7545850 CX488440 3' X. tropicalis NIH_XGC_tropGas7 whole organism NF stage 10.5 to NF stage 12.5
TTpA056b09 BX729579 3' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
IMAGE:8865751 EL703121 3' X. tropicalis NICHD_XGC_tropLimb_m limb NF stage 55 to NF stage 66
TTpA063b03 BX718980 3' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
IMAGE:8869089 EL709104 3' X. tropicalis NICHD_XGC_tropLimb_m limb NF stage 55 to NF stage 66
IMAGE:7790967 CX324525 3' X. tropicalis NIH_XGC_tropTad5 whole organism NF stage 35 and 36 to NF stage 41
IMAGE:7516447 CX747346 3' X. tropicalis NIH_XGC_tropNeu5 whole organism NF stage 14 to NF stage 18
TTpA054g15 BX735579 3' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
IMAGE:8892079 EL852216 3' X. tropicalis NICHD_XGC_trop_25 whole organism NF stage 25
TNeu055j13 BX685904 3' X. tropicalis XGC-neurula whole organism NF stage 13 to NF stage 21
TNeu078h22 BX687890 3' X. tropicalis XGC-neurula whole organism NF stage 13 to NF stage 21
TNeu089e20 BX693756 3' X. tropicalis XGC-neurula whole organism NF stage 13 to NF stage 21
TTbA037g11 CR418599 3' X. tropicalis XGC-tailbud whole organism NF stage 28 to NF stage 29 and 30
IMAGE:7618526 CX345918 3' X. tropicalis NIH_XGC_tropTad5 whole organism NF stage 35 and 36 to NF stage 41
IMAGE:8906548 EL799144 3' X. tropicalis NICHD_XGC_tropTail_m tail NF stage 55 to NF stage 66
TTpA068p05 BX721627 3' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
THdA018p22 CR581948 3' X. tropicalis XGC-tailbud-head head NF stage 28 to NF stage 29 and 30
TTpA068p09 BX721630 3' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
TTbA056n18 CR446276 3' X. tropicalis XGC-tailbud whole organism NF stage 28 to NF stage 29 and 30
IMAGE:7665540 CX850868 3' X. tropicalis NIH_XGC_tropBrn4 brain frog
TTbA006k08 CR416801 3' X. tropicalis XGC-tailbud whole organism NF stage 28 to NF stage 29 and 30
IMAGE:7747123 DN042901 3' X. tropicalis NIH_XGC_tropKid1 mesonephric kidney frog
TTpA022l05 BX702914 3' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
IMAGE:7698211 CX929895 3' X. tropicalis NIH_XGC_tropTe5 testis frog
TTpA005m01 BX706508 3' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
IMAGE:8921273 EL835472 3' X. tropicalis NICHD_XGC_tropTe1 testis frog
TTpA024c19 BX709804 3' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
TTpA024f04 BX714255 3' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
THdA024o22 CR571198 3' X. tropicalis XGC-tailbud-head head NF stage 28 to NF stage 29 and 30
CAAN11075 CX926604 3' X. tropicalis NIH_XGC_tropTe4 testis frog
TTpA063k03 BX716457 3' X. tropicalis XGC-tadpole whole organism NF stage 35 and 36 to NF stage 40
IMAGE:7650648 CX811666 3' X. tropicalis NIH_XGC_tropBrn2 brain frog
XL035k21 BJ042431 5' X. laevis.L NIBB Mochii normalized Xenopus neurula library whole organism NF stage 15
IMAGE:5514973 CF287647 5' X. laevis.L NICHD_XGC_Emb4 whole organism NF stage 31 to NF stage 32
IMAGE:5514206 CF290714 5' X. laevis.L NICHD_XGC_Emb4 whole organism NF stage 31 to NF stage 32
XL055n03 BJ070183 5' X. laevis.L NIBB Mochii normalized Xenopus tailbud library whole organism NF stage 25
za42h08 AW158572 5' X. laevis.L Xenopus EST library brain NF stage 45 to NF stage 66
IMAGE:6878672 CB180477 5' X. laevis.L NICHD_XGC_Tad1 whole organism NF stage 54 to prometamorphosis stage
IMAGE:8535588 EB464881 5' X. laevis.L NICHD_XGC_limb_m limb NF stage 54 to NF stage 61
PBX0147D01 AW645047 5' X. laevis.L Blackshear/Soares normalized Xenopus egg library egg unfertilized egg stage
IMAGE:3301240 BE132165 5' X. laevis.L Blackshear/Soares normalized Xenopus egg library egg unfertilized egg stage
IMAGE:4782984 BM260937 5' X. laevis.L Blackshear/Soares normalized Xenopus egg library egg unfertilized egg stage
IMAGp998A0110646 BX854513 5' X. laevis.L Soares NXEG egg unfertilized egg stage
IMAGp998E178086 BX854671 5' X. laevis.L Soares NXEG egg unfertilized egg stage
IMAGE:6324547 CA972683 5' X. laevis.L Wellcome CRC pSK egg egg unfertilized egg stage
IMAGE:6871223 CA983600 5' X. laevis.L Wellcome CRC pSK egg egg unfertilized egg stage
IMAGE:8530516 EB467280 5' X. laevis.L NICHD_XGC_int_m whole organism NF stage 56 to NF stage 62
XL158n08 BJ612332 5' X. laevis.L NIBB Mochii normalized Xenopus early gastrula library whole organism NF stage 10.5
XL159n08 BJ612615 5' X. laevis.L NIBB Mochii normalized Xenopus early gastrula library whole organism NF stage 10.5
XL176b08 BJ616208 5' X. laevis.L NIBB Mochii normalized Xenopus early gastrula library whole organism NF stage 10.5
XL217a10 BJ627106 5' X. laevis.L NIBB Mochii normalized Xenopus early gastrula library whole organism NF stage 10.5
IMAGp998B088351 BX843078 5' X. laevis.L Wellcome CRC pSK St 10 5 whole organism NF stage 10.5
xl224d05 DC100878 5' X. laevis.L Yamamoto/Hyodo-Miura NIBB/NBRP Xenopus DMZ pCS2p+ cDNA library Keller explant NF stage 10.5 to NF stage 15
xl255b16 DC110306 5' X. laevis.L Yamamoto/Hyodo-Miura NIBB/NBRP Xenopus DMZ pCS2p+ cDNA library Keller explant NF stage 10.5 to NF stage 15
xl274e21 DC115919 5' X. laevis.L Yamamoto/Hyodo-Miura NIBB/NBRP Xenopus DMZ pCS2p+ cDNA library Keller explant NF stage 10.5 to NF stage 15
XL031m13 BJ035058 5' X. laevis.L NIBB Mochii normalized Xenopus neurula library whole organism NF stage 15
IMAGE:8319345 DY560820 5' X. laevis.L NICHD_XGC_Emb10 whole organism NF stage 17 to NF stage 19
IMAGE:6877180 CB755798 3' X. laevis.L NICHD_XGC_Tad1 whole organism NF stage 54 to prometamorphosis stage
XL217a10 BJ643429 3' X. laevis.L NIBB Mochii normalized Xenopus early gastrula library whole organism NF stage 10.5
XL031m13 BJ051434 3' X. laevis.L NIBB Mochii normalized Xenopus neurula library whole organism NF stage 15
XL035k21 BJ056389 3' X. laevis.L NIBB Mochii normalized Xenopus neurula library whole organism NF stage 15
IMAGE:6878672 CB560218 3' X. laevis.L NICHD_XGC_Tad1 whole organism NF stage 54 to prometamorphosis stage
XL176b08 BJ632784 3' X. laevis.L NIBB Mochii normalized Xenopus early gastrula library whole organism NF stage 10.5
XL159n08 BJ629099 3' X. laevis.L NIBB Mochii normalized Xenopus early gastrula library whole organism NF stage 10.5
XL158n08 BJ628836 3' X. laevis.L NIBB Mochii normalized Xenopus early gastrula library whole organism NF stage 10.5
IMAGE:4782984 BM260874 3' X. laevis.L Blackshear/Soares normalized Xenopus egg library egg unfertilized egg stage
IMAGE:6877180 CB756462 3' X. laevis.L NICHD_XGC_Tad1 whole organism NF stage 54 to prometamorphosis stage
XL407p14ex BP730313 3' X. laevis.L Osada Taira anterior neuroectoderm (ANE) pCS105 cDNA library ectoderm NF stage 12.5