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Summary Expression Phenotypes Gene Literature (19) GO Terms (23) Nucleotides (182) Proteins (51) Interactants (704) Wiki
XB-GENEPAGE- 480378

Show:     All X. tropicalis X. laevis

Protein sequences for fzd10 - All


Models (34)

Source Version Model Species
NCBI 10.1 XBmRNA9943 X. laevis.S
NCBI 10.1 XBmRNA4891 X. laevis.L
NCBI 10.0 mRNA020470 X. tropicalis
Xenbase 9.2 rna38749 X. laevis.L
Xenbase 9.2 rna6784 X. laevis.S
Xenbase 9.1 rna27544 X. tropicalis
JGI 9.1 Xelaev18010581m X. laevis.S
JGI 9.1 Xelaev18007747m X. laevis.L
JGI 7.2 Xelaev16052682m X. laevis.L
JGI 7.2 Xelaev16019028m X. laevis.S
JGI 7.1 Xetro.A00753.1 X. tropicalis
JGI 6.0 XeXenL6RMv10038368m X. laevis.S
JGI 6.0 XeXenL6RMv10027847m X. laevis.L
JGI 6.0 XeXenL6RMv10031396m X. laevis.L
JGI 4.1 fgenesh1_pg.C_scaffold_577000013 X. tropicalis
JGI 4.1 fgenesh1_pm.C_scaffold_577000004 X. tropicalis
JGI 4.1 fgenesh1_Sanger_cdna.C_scaffold_577000004 X. tropicalis
JGI 4.1 e_gw1.577.24.1 X. tropicalis
JGI 4.1 gw1.577.25.1 X. tropicalis
JGI 4.1 gw1.577.26.1 X. tropicalis
JGI 4.1 gw1.577.24.1 X. tropicalis
JGI 4.1 e_gw1.577.25.1 X. tropicalis
JGI 4.1 e_gw1.577.26.1 X. tropicalis
ENSEMBL 4.1 ENSXETP00000006416 X. tropicalis
JGI 4.1 estExt_fgenesh1_kg.C_5770004 X. tropicalis
JGI 4.1 estExt_fgenesh1_pg.C_5770011 X. tropicalis
JGI 4.1 estExt_fgenesh1_pg.C_5770012 X. tropicalis
JGI 4.1 estExt_fgenesh1_pm.C_5770003 X. tropicalis
JGI 4.1 estExt_FilteredModels1.C_5770006 X. tropicalis
JGI 4.1 estExt_Genewise1.C_5770024 X. tropicalis
JGI 4.1 estExt_Genewise1.C_5770025 X. tropicalis
JGI 4.1 estExt_Genewise1.C_5770026 X. tropicalis
JGI 4.1 fgenesh1_kg.C_scaffold_577000004 X. tropicalis
JGI 4.1 fgenesh1_pg.C_scaffold_577000012 X. tropicalis

UniProtKB Protein Function: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt8. Could have an antagonizing activity in the morphogenesis during development.

AI Protein Function : The gene fzd10 encodes a frizzled class receptor that is membrane-bound and involved in Wnt signaling pathways. It plays a role in neural crest specification, contributing to the development of cranial ganglia and craniofacial cartilage. Expression is also detected in the neural tube, otic vesicle, and branchial arches during embryogenesis.

NCBI Proteins (17)

Accession Species Source
AAH74699 X. tropicalis NCBI Protein
CAJ83812 X. tropicalis NCBI Protein
KAE8634931 X. tropicalis RefSeq
NP_001005669 X. tropicalis RefSeq
AAI69883 X. laevis.L NCBI Protein
AAI69887 X. laevis.L NCBI Protein
BAB19017 X. laevis.L NCBI Protein
NP_001080925 X. laevis.L RefSeq
OCU01988 X. laevis.L NCBI Protein
AAD44332 X. laevis.S NCBI Protein
AAH72128 X. laevis.S NCBI Protein
BAB19018 X. laevis.S NCBI Protein
NP_001080926 X. laevis.S RefSeq
OCT98350 X. laevis.S NCBI Protein

UniProt Proteins (3)

Accession Species Source
Q6GL20 (InterPro) X. tropicalis TrEMBL
Q9DEB5 (InterPro) X. laevis.L Swiss-Prot
A0A974DVQ6 (InterPro) X. laevis.S TrEMBL