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Summary Expression Phenotypes Gene Literature (0) GO Terms (24) Nucleotides (235) Proteins (52) Interactants (39) Wiki
XB-GENEPAGE- 5960891

Show:     All X. tropicalis X. laevis

Protein sequences for rnf126 - All


Models (30)

Source Version Model Species
NCBI 10.1 XBmRNA3087 X. laevis.L
NCBI 10.1 XBmRNA8419 X. laevis.S
ENSEMBL 10.0 ENSXETP00000014317 X. tropicalis
ENSEMBL 10.0 ENSXETP00000118027 X. tropicalis
NCBI 10.0 mRNA016257 X. tropicalis
ENSEMBL 10.0 ENSXETP00000098255 X. tropicalis
Xenbase 9.2 rna53519 X. laevis.S
Xenbase 9.2 rna84174 X. laevis.L
Xenbase 9.1 rna16740 X. tropicalis
JGI 9.1 Xelaev18006461m X. laevis.L
ENSEMBL 9.1 ENSXETP00000014317 X. tropicalis
ENSEMBL 9.1 ENSXETP00000098255 X. tropicalis
JGI 9.1 Xelaev18009938m X. laevis.S
JGI 7.2 Xelaev16066858m X. laevis.S
JGI 7.2 Xelaev16056045m X. laevis.L
JGI 7.1 Xetro.A02078.2 X. tropicalis
JGI 7.1 Xetro.A02078.1 X. tropicalis
JGI 6.0 XeXenL6RMv10021110m X. laevis.L
JGI 6.0 XeXenL6RMv10009622m X. laevis.S
JGI 6.0 XeXenL6RMv10009622m X. laevis.L
JGI 4.1 gw1.529.47.1 X. tropicalis
JGI 4.1 fgenesh1_Sanger_cdna.C_scaffold_529000005 X. tropicalis
JGI 4.1 fgenesh1_pg.C_scaffold_529000052 X. tropicalis
JGI 4.1 e_gw1.529.47.1 X. tropicalis
JGI 4.1 fgenesh1_kg.C_scaffold_529000010 X. tropicalis
ENSEMBL 4.1 ENSXETP00000014317 X. tropicalis
JGI 4.1 e_gw1.529.49.1 X. tropicalis
JGI 4.1 e_gw1.529.48.1 X. tropicalis
JGI 4.1 gw1.529.49.1 X. tropicalis
JGI 4.1 gw1.529.48.1 X. tropicalis

UniProtKB Protein Function: E3 ubiquitin-protein ligase that mediates ubiquitination oF target proteins. Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates. Part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome. Probably acts by providing the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the hydrophobic mislocalized proteins and their targeting to the proteasome.

AI Protein Function : The gene rnf126 encodes an E3 ubiquitin-protein ligase involved in proteasome-mediated degradation of specific target proteins through the ubiquitination pathway. This protein localizes to the cytoplasm and nucleus, where its activity is associated with processes including neural crest cell migration, melanocyte development, and DNA damage response pathways interacting with the p53 protein.

NCBI Proteins (22)

Accession Species Source
AAH75492 X. tropicalis NCBI Protein
CAJ81894 X. tropicalis NCBI Protein
KAE8632123 X. tropicalis RefSeq
KAE8632124 X. tropicalis RefSeq
NP_001006735 X. tropicalis RefSeq
XP_012815252 X. tropicalis NCBI Protein
XP_031753815 X. tropicalis NCBI Protein
A0A8J0TVH9 X. laevis.S Uniprot
AAH70697 X. laevis.S NCBI Protein
NP_001084974 X. laevis.S RefSeq
OCT97709 X. laevis.S NCBI Protein
XP_018091647 X. laevis.S NCBI Protein
AAH56088 X. laevis.L NCBI Protein
NP_001079878 X. laevis.L RefSeq
OCU00682 X. laevis.L NCBI Protein
XP_041447104 X. laevis.L RefSeq

UniProt Proteins (7)

Accession Species Source
A0A6I8SXR5 (InterPro) X. tropicalis TrEMBL
A0A803KCE0 (InterPro) X. tropicalis TrEMBL
Q6DIP3 (InterPro) X. tropicalis Swiss-Prot
A0A8J0TVH9 (InterPro) X. laevis.S Uniprot
A0A974DT80 (InterPro) X. laevis.S TrEMBL
Q6IRP0 (InterPro) X. laevis.S Swiss-Prot
Q7T0Q3 (InterPro) X. laevis.L Swiss-Prot