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Summary Expression Phenotypes Gene Literature (0) GO Terms (36) Nucleotides (257) Proteins (68) Interactants (252) Wiki
XB-GENEPAGE- 962622

Show:     All X. tropicalis X. laevis

Protein sequences for nsun2 - All


Models (43)

Source Version Model Species
NCBI 10.1 XBmRNA54929 X. laevis.S
ENSEMBL 10.0 ENSXETP00000070353 X. tropicalis
ENSEMBL 10.0 ENSXETP00000059424 X. tropicalis
ENSEMBL 10.0 ENSXETP00000099267 X. tropicalis
NCBI 10.0 mRNA055519 X. tropicalis
Xenbase 9.2 rna26359 X. laevis.S
ENSEMBL 9.1 ENSXETP00000076775 X. tropicalis
ENSEMBL 9.1 ENSXETP00000076784 X. tropicalis
ENSEMBL 9.1 ENSXETP00000082008 X. tropicalis
ENSEMBL 9.1 ENSXETP00000090869 X. tropicalis
ENSEMBL 9.1 ENSXETP00000099267 X. tropicalis
ENSEMBL 9.1 ENSXETP00000100666 X. tropicalis
Xenbase 9.1 rna25925 X. tropicalis
JGI 9.1 Xelaev18033356m X. laevis.S
ENSEMBL 9.1 ENSXETP00000003620 X. tropicalis
ENSEMBL 9.1 ENSXETP00000059424 X. tropicalis
ENSEMBL 9.1 ENSXETP00000065244 X. tropicalis
ENSEMBL 9.1 ENSXETP00000070353 X. tropicalis
JGI 8.0 Xetrov14027392m X. tropicalis
JGI 7.2 Xelaev16003158m X. laevis.S
JGI 7.1 Xetro.F00960.1 X. tropicalis
JGI 7.1 Xetro.F00960.2 X. tropicalis
JGI 7.1 Xetro.F00960.3 X. tropicalis
JGI 7.1 Xetro.F00960.4 X. tropicalis
JGI 7.1 Xetro.F00960.5 X. tropicalis
JGI 6.0 XeXenL6RMv10013359m X. laevis.S
JGI 4.1 fgenesh_pm_kg.C_scaffold_46000003 X. tropicalis
JGI 4.1 gw1.46.190.1 X. tropicalis
JGI 4.1 gw1.46.210.1 X. tropicalis
JGI 4.1 gw1.46.5.1 X. tropicalis
JGI 4.1 estExt_Genewise1.C_460005 X. tropicalis
JGI 4.1 estExt_FilteredModels1.C_460006 X. tropicalis
JGI 4.1 e_gw1.46.190.1 X. tropicalis
ENSEMBL 4.1 ENSXETP00000003620 X. tropicalis
JGI 4.1 e_gw1.46.5.1 X. tropicalis
JGI 4.1 e_gw1.46.210.1 X. tropicalis
JGI 4.1 estExt_fgenesh1_pg.C_460010 X. tropicalis
JGI 4.1 estExt_fgenesh1_kg.C_460003 X. tropicalis
JGI 4.1 estExt_Genewise1.C_460189 X. tropicalis
JGI 4.1 estExt_Genewise1.C_460207 X. tropicalis
JGI 4.1 fgenesh1_kg.C_scaffold_46000003 X. tropicalis
JGI 4.1 fgenesh1_Sanger_cdna.C_scaffold_46000002 X. tropicalis
JGI 4.1 fgenesh1_pg.C_scaffold_46000010 X. tropicalis

UniProtKB Protein Function: RNA cytosine C(5)-methyltransferase that methylates cytosine to 5-methylcytosine (m5C) in various RNAs, such as tRNAs, mRNAs and some long non-coding RNAs (lncRNAs). Involved in various processes, such as epidermal stem cell differentiation, testis differentiation and maternal to zygotic transition during early development: acts by increasing protein synthesis; cytosine C(5)-methylation promoting tRNA stability and preventing mRNA decay. Methylates cytosine to 5-methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. tRNA methylation is required generation of RNA fragments derived from tRNAs (tRFs). Also mediates C(5)-methylation of mitochondrial tRNAs. Catalyzes cytosine C(5)-methylation of mRNAs, leading to stabilize them and prevent mRNA decay. Cytosine C(5)-methylation of mRNAs also regulates mRNA export. Also mediates cytosine C(5)-methylation of non-coding RNAs, such as vault RNAs (vtRNAs), promoting their processing into regulatory small RNAs. Required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.

AI Protein Function : The nsun2 protein is an RNA methyltransferase that catalyzes cytosine-5 methylation in various RNA substrates, including tRNA and mRNA, which can influence RNA stability and translation. It localizes to the nucleus and mitochondria. Its function is required for proper neural crest development and the differentiation of melanocytes from neural crest cells.

NCBI Proteins (25)

Accession Species Source
AAI71126 X. tropicalis NCBI Protein
CAJ83692 X. tropicalis NCBI Protein
KAE8597606 X. tropicalis RefSeq
KAE8597607 X. tropicalis RefSeq
KAE8597608 X. tropicalis RefSeq
KAE8597609 X. tropicalis RefSeq
KAE8597610 X. tropicalis RefSeq
KAE8597611 X. tropicalis RefSeq
KAE8597612 X. tropicalis RefSeq
KAE8597613 X. tropicalis RefSeq
KAE8597614 X. tropicalis RefSeq
KAE8597615 X. tropicalis RefSeq
NP_001015962 X. tropicalis RefSeq
XP_012820119 X. tropicalis NCBI Protein
XP_012820120 X. tropicalis NCBI Protein
AAH68818 X. laevis.S NCBI Protein
AAH97814 X. laevis.S NCBI Protein
NP_001084513 X. laevis.S RefSeq
OCT74381 X. laevis.S NCBI Protein
XP_018124146 X. laevis.S NCBI Protein
XP_041423046 X. laevis.S RefSeq

UniProt Proteins (4)

Accession Species Source
Q28E61 (InterPro) X. tropicalis Swiss-Prot
A0A1L8FS47 (InterPro) X. laevis.S TrEMBL
A0A974CLH3 (InterPro) X. laevis.S TrEMBL
Q4V7N2 (InterPro) X. laevis.S TrEMBL