|
Display additional annotations [+]
Gene |
Clone |
Species |
Stages |
Anatomy |
hoxc6
|
|
laevis
|
NF stage 12
to
NF stage 12.5
|
marginal zone
,
ventral marginal zone
,
ventro-lateral marginal zone
,
dorso-lateral marginal zone
,
dorsal marginal zone
,
[+]
|
hoxc6
|
|
laevis
|
NF stage 11.5
|
ventral marginal zone
,
ventro-lateral marginal zone
,
dorso-lateral marginal zone
,
non-involuting marginal zone
|
hoxc6
|
|
laevis
|
NF stage 10.5
to
NF stage 11
|
|
hoxd1
|
|
laevis
|
NF stage 10.5
to
NF stage 11.5
|
neuroectoderm
,
marginal zone
,
ventral marginal zone
,
ventro-lateral marginal zone
,
dorso-lateral marginal zone
,
[+]
|
hoxd1
|
|
laevis
|
NF stage 12
to
NF stage 12.5
|
mesoderm
,
marginal zone
,
ventral marginal zone
,
ventro-lateral marginal zone
,
dorso-lateral marginal zone
,
[+]
|
hoxa7
|
|
laevis
|
NF stage 11.5
to
NF stage 12.5
|
ventral marginal zone
,
ventro-lateral marginal zone
,
dorso-lateral marginal zone
,
circumblastoporal collar
,
non-involuting marginal zone
|
hoxa7
|
|
laevis
|
NF stage 10.5
to
NF stage 11
|
|
hoxb4
|
|
laevis
|
NF stage 12
to
NF stage 12.5
|
dorso-lateral marginal zone
,
circumblastoporal collar
,
posterior
|
hoxb4
|
|
laevis
|
NF stage 11
to
NF stage 11.5
|
marginal zone
,
ventral marginal zone
,
ventro-lateral marginal zone
,
dorso-lateral marginal zone
|
hoxb4
|
|
laevis
|
NF stage 10.5
|
|
|
|
Fig. 4. Temporal collinearity In the Xenopus gastrula. The figure shows Hox ex- pression patterns at sequential stages during gastrulation in Xenopus. The embryos are seen from underneath, where a ring (the blastopore) shows the position where mesoderm tissue invaginates during gastrulation. This ring gets smaller as gastrulation proceeds and the upper tissues in the embryo spread out and cover the lower part of the embryo (epiboly). The expression of several different Hox genes, seen as blue colour by in situ hybridisation, is in each case initially in the gastrula mesoderm in the zone above (outside) the ring. Hox expression is thus seen as a blue ring, and since it is initially only in part of the mesoderm, the ring is initially broken. The ring of Hox expression gets smaller as the blatopore ring gets smaller and mesoderm invaginates into the embryo.The figure shows expression of a sequence of Hox genes with differ- ent paralogue numbers, from 1 to 9. It will be seen that the Hox gene with the lowest paralogue number starts expression first and later numbers start sequentially later. It will also be seen that the Hox genes in this time sequence include members of all of the 4 primary vertebrate paralogue groups (a,b,c,d). |