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Gene/CloneSpeciesStageAnatomy ItemExperimenter
lmnb1xenopus retinal stem cell region 

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Experiment details for lmnb1

Local translation of extranuclear lamin B promotes axon maintenance.

Local translation of extranuclear lamin B promotes axon maintenance.

Gene Clone Species Stages Anatomy
lmnb1.L laevis NF stage 40 to NF stage 45 retinal stem cell region

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  Figure 3. LB2 mRNA and Protein Are Expressed in RGC Axons and GCs(A) Axonal lb2 mRNA detected by RT-PCR.(B and C) Lb2 FISH in cultured retinal axons and its quantitation (mean ± SEM; n = no. of GC; ∗p < 0.05; Mann-Whitney).(D–G′) ISH of stage 40–45 embryo sections (RGC: retinal ganglion cell layer; ONH: optic nerve head; and IPL/OPL: inner/outer plexiform layer). The same sections were counterstained for neurofilament and DAPI.(H and I) LB2 immunostaining in cultured retinal axons and its reduction by LB2MO.(J and K′) Immunostaining in tissue sections. The boxed areas are shown in the lower panels.Scale bars, 5 μm in (B) and (H), 25 μm in (D)–(G), (J), and (K), and 10 μm in (J) and (K) lower panels. See also Figure S3.