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mpoxenopus blastema 

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Experiment details for mpo

Mescher AL et al. (2013) Assay

Changes in the inflammatory response to injury and its resolution during the loss of regenerative capacity in developing Xenopus limbs.

Gene Clone Species Stages Anatomy
mpo.L laevis NF stage 53 to NF stage 57 blastema

  Figure 1. Whole-mounts of stage 53 and stage 57 Xenopus hindlimbs from 0 hours to 5 days post-amputation (PA) stained by enzyme histochemistry for myeloperoxidase (MPO), a marker for neutrophils and macrophages. Only background staining is visible at the time of amputation (0 hPA), but by 6 hPA in limbs of both stages the number of brown MPO+ cells increase greatly near the site of amputation. MPO staining diminished slowly through 5 dPA in limbs of both stages. The larger, very dark structures are melanocytes.