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Search Criteria

Gene/Clone	Species	Stage	Anatomy Item	Experimenter
dlx5	xenopus		neuroectoderm [+] midbrain-hindbrain boundary,mandibular crest,hyoid crest,branchial crest,neuroectoderm outer layer,neuroectoderm inner layer,pre-chordal neural plate,chordal neural plate,notoplate,neural crest,lens placode,neural groove,neural plate,neurocoel,sensorial layer of neurectoderm,cranial placode,anterior neural fold,trunk neural crest,cranial neural crest,Rohon-Beard neuron,migratory neural crest cell,neural fold,optic field,preplacodal ectoderm,pre-chordal neural plate border,chordal neural plate border,neural plate border,anterior branchial crest,posterior branchial crest,cardiac neural crest,vagal neural crest,sacral neural crest,anterior placodal area,posterior placodal area,anterior neural ridge,postmigratory neural crest cell,premigratory neural crest cell,isthmic nucleus,forebrain-midbrain boundary,lateral preplacodal ectoderm,superficial layer of neurectoderm,posterior neural fold,migratory trunk neural crest cell,anterior neuroectoderm,chordal neural crest,Bowman's gland,Mauthner cell,Muller cell,Rathke's pouch,accessory olfactory bulb,adenohypophysis,afferent neuron,amacrine cell,amphibian papilla,amygdala,anterior amygdala,anterior branchial crest,anterior commissure,anterior crista,anterior entopeduncular nucleus,anterior entopeduncular region,anterior hypothalamus,anterior neural fold,anterior neural tube,anterior placodal area,anterior tectum,anterior thalamic nucleus,anterodorsal tegmental nucleus,anteroventral tegmental nucleus,astrocyte,astrocyte end-foot,auditory hair cell,auditory ossicle,auditory tube,basal forebrain,basal ganglion,basilar papilla,bed nucleus of the stria terminalis,bipolar neuron,brain ventricle,branchial crest,buccopharyngeal membrane,cardiac neural crest,caudal tuberal region,cell body layer of the optic tectum,central amygdala,central canal,central nucleus of the thalamus,central retina,cerebellum,chordal neural crest,chordoneural hinge,choroid,choroid fissure,ciliary body,ciliary marginal zone,conjunctiva,cornea,cranial neural crest,diencephalon,dorsal column nucleus,dorsal fin margin,dorsal funiculus,dorsal habenular nucleus,dorsal pallidum,dorsal pallium,dorsal septum,dorsal tegmentum,dorsal telencephalon,dorsal thalamus,dorsolateral neural tube,efferent neuron,eminentia thalami,endolymphatic duct,enteric neuron,ethmoid bone,external plexiform layer of the olfactory bulb,eye photoreceptor cell,floor plate,footplate of the stapes,forebrain,forebrain-midbrain boundary,fourth ventricle,frontal nerve,globe,glomerular layer of the olfactory bulb,granule cell,granule cell layer of the cerebellum,granule cell layer of the olfactory bulb,habenula,hindbrain,horizontal cell,hyoid crest,hypophysis,hypothalamus,infundibulum,inner ear,inner limiting membrane,interneuron,iris,isthmic nucleus,lagena,lateral amygdala,lateral crista,lateral forebrain bundle,lateral funiculus,lateral ganglionic eminence,lateral hypothalamic nucleus,lateral pallium,lateral preplacodal ectoderm,lateral septum,laterodorsal tegmental nucleus,lens,lens epithelium,lens fiber cell mass,lens placode,lens transitional zone,locus coeruleus,lower eyelid,magnocellular preoptic nucleus,mammilary region,mandibular crest,mandibular nerve,maxillary nerve,medial amygdala,medial ganglionic eminence,medial pallium,medial septum,medulla oblongata,melanotrope,mesencephalic artery,mesencephalic vein,metencephalic artery,metencephalic vein,midbrain,midbrain tegmentum,midbrain-hindbrain boundary,middle ear,migratory neural crest cell,migratory trunk neural crest cell,mitral cell,mitral cell layer of the olfactory bulb,nasociliary nerve,neural stem cell,neurenteric canal,neurohypophysis,neuropil of the optic tectum,nucleus accumbens,nucleus of the diagonal band,nucleus of the solitary tract,nucleus reticularis inferior,nucleus reticularis medialis,nucleus reticularis superior,oculomotor motornucleus,olfactory bulb,olfactory sensory neuron,oligodendrocyte,optic chiasm,optic disc,optic fiber layer,optic nerve,optic stalk,optic tectum,optic tract,oral cavity,oral epithelium,osseous labyrinth,otic capsule,outer limiting membrane,oval window,pallidum,pallium,pars distalis,pars externa of the stapes,pars intermedia,pars interna of the stapes,pars media of the stapes,pars nervosa,peripheral nerve,peripheral retina,photoreceptor layer,pia mater,pial cell,pigment layer,pineal gland,posterior branchial crest,posterior commissure,posterior crista,posterior hypothalamus,posterior neural fold,posterior neural tube,posterior placodal area,posterior tectum,posterior wall of neurenteric canal,posterodorsal tegmental nucleus,posteroventral tegmental nucleus,postmigratory neural crest cell,premigratory neural crest cell,preoptic area,preplacodal ectoderm,pretectum,prethalamus,prethalamus basal plate,processus retroarticularis of Meckel's cartilage,prootic bone,prosomere,prosomere 4,prosomere 5,prosomere 6,pupil,radial glial cell,raphe nucleus,retina,retinal ganglion cell,retinal ganglion cell layer,retinal inner nuclear layer,retinal inner plexiform layer,retinal layer,retinal neural layer,retinal outer nuclear layer,retinal outer plexiform layer,retinal pigmented epithelium,retinal progenitor cell,retinal progenitor cell region,retinal stem cell,retinal stem cell region,retromammillary area,rhombic lip,rhombomere,roof of mouth,roof plate,rostral tuberal region,saccular macula,sacral neural crest,sclera,semicircular canal,solitary tract,spinal neuron,spiral septum,stapes,stria terminalis,striatum,subcommissural organ,subpallium,subthalamic nucleus,sulcus limitans of neural tube,suprachiasmatic nucleus,supraoptoparaventricular region,telencephalon,telencephalon septum,thalamus,third ventricle,torus semicircularis,trochlear motornucleus,trunk neural crest,tuberal region,tympanic annulus,tympanic disk,vagal neural crest,ventral funiculus,ventral habenular nucleus,ventral hypothalamic nucleus,ventral pallidum,ventral pallium,ventral septum,ventral tegmentum,ventricular layer of the optic tectum,ventricular outflow tract,ventricular zone,ventrolateral neural tube,ventrolateral thalamic nucleus,ventromedial thalamic nucleus,vestibular apparatus,vestibule,zona limitans intrathalamica,Jacobson's organ,Meckel's cartilage,Rathke's pouch,adrenal medulla,afferent neuron,anterior branchial crest,anterior lateral line ganglion,anterior lateral line placode,anterior neural ridge,anterior neural tube,anterodorsal lateral line placode,aortic arch,astrocyte,astrocyte end-foot,auditory apparatus,brain,branchial crest,buccopharyngeal membrane,ceratohyal,choana,choroid fissure,circumpharyngeal ridge,cranial ganglion,cranial neural crest,cranial placode,craniofacial skeleton,dorsal tail fin,dorsal tegmentum,dorsolateral neural tube,efferent neuron,enteric nervous system,enteric neuron,eye,eye primordium,floor plate,forebrain,gasserian ganglion,glial cell,hindbrain,hyoid crest,hyomandibular lateral line,hypophyseal primordium,hypophysis,infraorbital lateral line,infraorbital lateral line primordium,iris,lateral line placode,lateral preplacodal ectoderm,lens,lens placode,mandibular crest,melanoblast,melanophore,midbrain,migratory neural crest cell,mouth,mouth primordium,neural crest,neural fold,neural groove,neural stem cell,neural tube,neurogenic placode,non-neurogenic ectodermal placode,occipital lateral line,oculomotor motornucleus,olfactory epithelium,olfactory nerve,olfactory organ,olfactory pit,olfactory placode,oligodendrocyte,optic nerve,optic stalk,optic tectum,optic vesicle,otic capsule,otic placode,otic vesicle,outflow tract,palatoquadrate,peripheral ganglion,pigment cell,posterior branchial crest,posterior neural tube,preplacodal ectoderm,radial glial cell,roof plate,sensorial layer of neurectoderm,spinal cord,stomodeal-hypophyseal primordium,superficial layer of neurectoderm,supraorbital lateral line,tooth,trigeminal ganglion,trigeminal nerve,trigeminal placode,trunk lateral line,ventral tegmentum,ventrolateral neural tube,vestibulocochlear ganglion

Too many results?Too few results?

Expression summary for dlx5

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Experiment	Species	Images	Stages	Anatomy	Assay
Harland lab in situ screen Assay Harland Lab	tropicalis	1 image	NF stage 26	anterior branchial crest, diencephalon, dorsal fin margin, forebrain, hypothalamus, [+] otic placode, posterior branchial crest, profundal placode	in situ hybridization
Seufert DW et al. (2005) Assay Paper	laevis	1 image	NF stage 26	brain, forebrain, neural plate, neuroectoderm, olfactory placode	in situ hybridization
Illes JC et al. (2009) Assay Paper	tropicalis	1 image	NF stage 31	diencephalon, forebrain, hypothalamus, lateral ganglionic eminence, medial ganglionic eminence, [+] stomodeal-hypophyseal primordium, telencephalon	in situ hybridization
Harland Lab Assay Harland Lab	tropicalis	3 images	NF stage 14 to NF stage 32	adenohypophyseal placode, chordal neural plate, chordal neural plate border, ciliary marginal zone, diencephalon, [+] dorsal fin margin, floor plate, forebrain, neural crest, neural plate, neural plate border, otic placode, otic vesicle, posterior placodal area, pre-chordal neural plate, pre-chordal neural plate border, spinal cord	in situ hybridization
Transgenic Xenopus embryos reveal that anterior neural development requires continued suppression of BMP signaling after gast... Paper	laevis	2 images	NF stage 15 to NF stage 19	anterior placodal area, cranial neural crest, neural tube, posterior placodal area	in situ hybridization
Differential distribution of competence for panplacodal and neural crest induction to non-neural and neural ectoderm. Paper	laevis	2 images	NF stage 18	anterior placodal area, chordal neural plate border, neural plate, neural plate border, pre-chordal neural plate border	in situ hybridization
Early neural crest induction requires an initial inhibition of Wnt signals. Paper	laevis	3 images	NF stage 11.5 to NF stage 15	anterior neural ridge, chordal neural plate border, neural groove, neural plate border, pre-chordal neural plate border	in situ hybridization
ΔNp63 is regulated by BMP4 signaling and is required for early epidermal development in Xenopus. Paper	laevis	1 image	NF stage 17	preplacodal ectoderm	in situ hybridization
The Xenopus Emx genes identify presumptive dorsal telencephalon and are induced by head organizer signals. Paper	laevis	1 image	NF stage 14	neuroectoderm, pre-chordal neural plate	in situ hybridization
Phylogenetic footprinting and genome scanning identify vertebrate BMP response elements and new target genes. Paper	laevis	1 image	NF stage 18 to NF stage 28	anterior placodal area, diencephalon, dorsal fin margin, forebrain, neural crest, [+] otic vesicle, posterior placodal area, preplacodal ectoderm	in situ hybridization
Chen JA et al. (2005) Assay Paper	tropicalis	1 image	NF stage 17 to NF stage 29 and 30	anterior neural ridge, forebrain, mandibular crest, neural plate border, pineal gland	in situ hybridization
Voigt J et al. (2005) Assay Paper	tropicalis	1 image	NF stage 17 to NF stage 26	adenohypophyseal placode, cranial neural crest, forebrain, migratory neural crest cell, neural plate border, [+] otic vesicle, posterior placodal area	in situ hybridization
A restrictive role for Hedgehog signalling during otic specification in Xenopus. Paper	laevis	1 image	NF stage 35 and 36	forebrain, otic vesicle	in situ hybridization
A restrictive role for Hedgehog signalling during otic specification in Xenopus. Paper	laevis	1 image	NF stage 35 and 36	brain, forebrain, otic vesicle	in situ hybridization
Differential regulation of Dlx gene expression by a BMP morphogenetic gradient. Paper	laevis	2 images	NF stage 13 to NF stage 20	chordal neural plate border, neural fold, neural plate border	in situ hybridization
Conserved and divergent patterns of Reelin expression in the zebrafish central nervous system.	laevis	1 image	NF stage 50	brain, diencephalon, forebrain	immunohistochemistry
Xenopus Distal-less related homeobox genes are expressed in the developing forebrain and are induced by planar signals. Paper	laevis	1 image	NF stage 16 to NF stage 33 and 34	anterior neural fold, brain, forebrain, neural plate, olfactory placode, [+] otic vesicle	in situ hybridization
GABAergic specification in the basal forebrain is controlled by the LIM-hd factor Lhx7. Paper	laevis	1 image	NF stage 35 and 36	diencephalon, lateral ganglionic eminence, medial ganglionic eminence, prethalamus, subpallium, [+] zona limitans intrathalamica	in situ hybridization
Evidences for tangential migrations in Xenopus telencephalon: developmental patterns and cell tracking experiments.	laevis	1 image	NF stage 48	brain, medial ganglionic eminence, subpallium	immunohistochemistry
Misexpression of Polycomb-group proteins in Xenopus alters anterior neural development and represses neural target genes. Paper	laevis	1 image	NF stage 19 to NF stage 26	anterior neural fold, forebrain, otic placode	in situ hybridization
Square T et al. (2014) Assay Paper	laevis	2 images	NF stage 33 and 34 to NF stage 37 and 38	brain, olfactory bulb, otic vesicle	in situ hybridization
Xenopus Distal-less related homeobox genes are expressed in the developing forebrain and are induced by planar signals. Paper	laevis	1 image	NF stage 27 to NF stage 28	forebrain, otic vesicle	in situ hybridization
Papalopulu N and Kintner C (1993) Assay Paper	laevis	1 image	NF stage 37 and 38	anterior hypothalamus, brain, diencephalon, forebrain, neural crest, [+] olfactory placode, otic vesicle, posterior hypothalamus, telencephalon, thalamus	in situ hybridization
Griffin JN et al. (2015) Assay Paper	tropicalis	2 images	NF stage 28	cranial neural crest, hyoid crest, mandibular crest, neural crest, olfactory placode	in situ hybridization
Xenopus Nkx6.3 is a neural plate border specifier required for neural crest development. Paper	laevis	1 image	NF stage 16	neural plate border	in situ hybridization
Fredieu JR et al. (1997) Assay Paper	laevis	1 image	NF stage 32	forebrain	in situ hybridization
Pa2G4 is a novel Six1 co-factor that is required for neural crest and otic development. Paper	laevis	1 image	NF stage 28	forebrain, optic vesicle, otic vesicle, telencephalon	in situ hybridization
Pa2G4 is a novel Six1 co-factor that is required for neural crest and otic development. Paper	laevis	1 image	NF stage 28	cranial neural crest, forebrain, migratory neural crest cell, neural crest, olfactory placode, [+] postmigratory neural crest cell, telencephalon	in situ hybridization
Differential and overlapping expression patterns of X-dll3 and Pax-6 genes suggest distinct roles in olfactory system develo... Paper	laevis	1 image	NF stage 15 to NF stage 29 and 30	olfactory epithelium	in situ hybridization
Six1 proteins with human branchio-oto-renal mutations differentially affect cranial gene expression and otic development. Paper	laevis	1 image	NF stage 28 to NF stage 32	forebrain, otic vesicle	in situ hybridization
Tavares ALP et al. (2021) Assay Paper	laevis	1 image	NF stage 28 to NF stage 33 and 34	forebrain, otic vesicle, pineal gland	in situ hybridization
Baxi AB et al. (2023) Assay Paper	laevis	1 image	NF stage 33 and 34	eye, forebrain, otic vesicle	in situ hybridization
NICHD_XGC_olfb Unigene laevis cDNA library Xenopus IMAGE cDNA Library	laevis		unspecified stage	brain	cDNA Library

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