XB-ART-50611Curr Biol 2014 Aug 18;2416:R746-9. doi: 10.1016/j.cub.2014.07.006.
Show Gene links Show Anatomy links
Multiciliogenesis: multicilin directs transcriptional activation of centriole formation.
During differentiation of multiciliated cells, numerous centrioles are generated in each cell to act as templates for the formation of a corresponding number of cilia. A new study reveals that multicilin, a protein required for multiciliogenesis, is a key component of a regulatory complex that activates the transcription of genes required for centriole formation.
PubMed ID: 25137586
Article link: Curr Biol
Species referenced: Xenopus
Genes referenced: mcidas