Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-1272
Cell 2005 Oct 07;1231:3-5. doi: 10.1016/j.cell.2005.09.015.
Show Gene links Show Anatomy links

A cellular response to an internal energy crisis.

Lipinski MM , Yuan J .


???displayArticle.abstract???
Lack of an appropriate energy supply has been thought to induce cell death in a nonspecific manner by causing a decline in metabolism and a gradual cessation of cellular function. In this issue of Cell, Nutt et al. (2005) describe a new mechanism that directly links nutrient availability to apoptosis in Xenopus oocytes and show that age-dependent changes in the nutritional state of a cell might lead to caspase activation and apoptotic cell death.

???displayArticle.pubmedLink??? 16213206
???displayArticle.link??? Cell


Species referenced: Xenopus laevis
Genes referenced: tbx2

References :
Nutt, Metabolic regulation of oocyte cell death through the CaMKII-mediated phosphorylation of caspase-2. 2005, Pubmed, Xenbase