XB-ART-1272
Cell
2005 Oct 07;1231:3-5. doi: 10.1016/j.cell.2005.09.015.
Show Gene links
Show Anatomy links
A cellular response to an internal energy crisis.
???displayArticle.abstract???
Lack of an appropriate energy supply has been thought to induce cell death in a nonspecific manner by causing a decline in metabolism and a gradual cessation of cellular function. In this issue of Cell, Nutt et al. (2005) describe a new mechanism that directly links nutrient availability to apoptosis in Xenopus oocytes and show that age-dependent changes in the nutritional state of a cell might lead to caspase activation and apoptotic cell death.
???displayArticle.pubmedLink??? 16213206
???displayArticle.link??? Cell
Species referenced: Xenopus laevis
Genes referenced: tbx2
References :
Nutt,
Metabolic regulation of oocyte cell death through the CaMKII-mediated phosphorylation of caspase-2.
2005, Pubmed,
Xenbase