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XB-ART-27501
Neurosci Lett 1988 May 16;881:39-44. doi: 10.1016/0304-3940(88)90312-6.
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Influence of the patch pipette glass on single acetylcholine channels recorded from Xenopus myocytes.

Rojas L , Zuazaga C .


Abstract
The type of glass used to fabricate patch pipettes influences the kinetic properties of single-channel currents activated by acetylcholine in Xenopus myocytes. In patches formed with hard glass pipettes, the opening rate decreased in a time-dependent manner. Such decrease was most pronounced for the low-conductance channel. In addition, longer-duration events of this form of channel dropped out faster than shorter-duration events and, as a consequence, the apparent channel open time became shorter during the recording period. These effects were not observed in patches formed with soft glass pipettes.

PubMed ID: 3399130
Article link: Neurosci Lett
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