Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-28769
Science 1986 Feb 07;2314738:613-6.
Show Gene links Show Anatomy links

Expression of an epidermal antigen used to study tissue induction in the early Xenopus laevis embryo.

Akers RM , Phillips CR , Wessells NK .


???displayArticle.abstract???
A monoclonal antibody (Epi 1) has been produced that recognizes an antigen expressed in epidermal cells of Xenopus laevis embryos. The Epi 1 antigen appears in embryonic epidermis at the end of gastrulation and is not expressed in nonepidermal structures derived from ectoderm (for example, neural tube or cement gland). The capacity to express the Epi 1 antigen is restricted to cells of the animal hemisphere prior to the midblastula stage of development (stage 8), and tissue interactions during gastrulation inhibit the expression of the Epi 1 antigen in neural ectoderm. This epidermal antigen will be a valuable marker for studies of ectodermal commitment.

???displayArticle.pubmedLink??? 3945801
???displayArticle.link??? Science
???displayArticle.grants??? [+]