XB-ART-17847
Nature
1996 Aug 15;3826592:595-601. doi: 10.1038/382595a0.
Show Gene links
Show Anatomy links
Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer.
???displayArticle.abstract???
An abundant cDNA enriched in Spemann's organizer, cerberus, was isolated by differential screening. It encodes a secreted protein that is expressed in the anterior endomesoderm. Microinjection of cerberus mRNA into Xenopus embryos induces ectopic heads, and duplicated hearts and livers. The results suggest a role for a molecule expressed in the anterior endoderm in the induction of head structures in the vertebrate embryo.
???displayArticle.pubmedLink??? 8757128
???displayArticle.link??? Nature
Species referenced: Xenopus
Genes referenced: cer1