XB-ART-18896
Nature
1995 Dec 07;3786557:578-83. doi: 10.1038/378578a0.
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Nucleation of microtubule assembly by a gamma-tubulin-containing ring complex.
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The highly conserved protein gamma-tubulin is required for microtubule nucleation in vivo. When viewed in the electron microscope, a highly purified gamma-tubulin complex from Xenopus consisting of at least seven different proteins is seen to have an open ring structure. This complex acts as an active microtubule-nucleating unit which can cap the minus ends of microtubules in vitro.
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Species referenced: Xenopus
Genes referenced: tubg1