Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
Interaction between motor axons from two different nerves reinnervating the pectoral muscle of Xenopus laevis.
Haimann C
,
Mallart A
,
Ferré JT
,
Zilber-Gachelin NF
.
Abstract
1. An electrophysiological and morphological study of sprouting and regeneration of motor nerves has been performed in the dually innervated pectoral muscle of Xenopus laevis. 2. Section of one of the nerves induced axon sprouting in the intact nerve. Synapse formation by the sprouting axons was slow since the intact nerve took more than 3 months to increase its field of innervation by 70%. The rate of axon regeneration was faster than that of axon sprouting since the cut nerve reinnervated its former territory in less than 1 month. 3. At early stages of synapse formation the sprouted or regenerated endings were poorly branched but any terminal branches were, as a rule, longer than normal. Signs of degeneration and replacement of endings have been observed. 4. Low levels of transmitter release persisted for several months in newly formed endings. This depression was more pronounced at the endings formed outside the normal field of innervation of the nerve. 5. Poly-innervated muscle fibres have been observed during reinnervation by regenerated or sprouted axons. Their number decreases gradually in the months that follow the beginning of reinnervation. Synaptic efficacy was lower at poly than at mono-innervated muscle fibres. At doubly innervated spots and at separated spots on the same fibre average end-plate potential (e.p.p.) amplitude was 1/3 and 2/3 respectively of that recorded at singly innervated fibres. 6. Electrophysiological and morphological data have been compared at individual doubly innervated end-plate sites. End-plate potential amplitude was positively correlated with the degree of ending development. 7. Sprouted endings remain functional after periods of reinnervation of 30 months, although signs of regression have been observed. These are probably mediated by spontaneous degeneration of the terminals and replacement by endings from the regenerating nerve.
Angaut-Petit,
Dual innervation of end-plate sites and its consequences for neuromuscular transmission in muscles of adult Xenopus laevis.
1979, Pubmed,
Xenbase
Angaut-Petit,
Dual innervation of end-plate sites and its consequences for neuromuscular transmission in muscles of adult Xenopus laevis.
1979,
Pubmed
,
Xenbase
Bennett,
A statistical analysis of the release of acetylcholine at newly formed synapses in striated muscle.
1974,
Pubmed
Bennett,
The formation and regression of synapses during the re-innervation of axolotl striated muscles.
1977,
Pubmed
Bennett,
The regression of synapses formed by a foreign nerve in a mature axolotl striated muscle.
1979,
Pubmed
Berndt,
The accumulation of C14-dinitrophenol by slices of rabbit kidney cortex.
1968,
Pubmed
BIRKS,
Physiological and structural changes at the amphibian myoneural junction, in the course of nerve degeneration.
1960,
Pubmed
Brown,
Sprouting and regression of neuromuscular synapses in partially denervated mammalian muscles.
1978,
Pubmed
Card,
Physiological alterations of rat extensor digitorum longus motor nerve terminals as a result of surgical denervation.
1977,
Pubmed
Chung,
Effect of cations on transport of weak organic acids in rabbit kidney slices.
1970,
Pubmed
COPENHAVER,
Intracellular accumulation as an active process in a mammalian renal transport system in vitro; energy dependence and competitive phenomena.
1956,
Pubmed
CROSS,
Renal tubular transport: accumulation of p-aminohippurate by rabbit kidney slices.
1950,
Pubmed
Dennis,
Formation and elimination of foreign synapses on adult salamander muscle.
1978,
Pubmed
Dennis,
Characteristics of transmitter release at regenerating frog neuromuscular junctions.
1974,
Pubmed
Diamond,
Trophic regulation of nerve sprouting.
1976,
Pubmed
EDDS,
Collateral nerve regeneration.
1953,
Pubmed
Fangboner,
Formation and regression of inappropriate nerve sprouts during trochlear nerve regeneration in Xenopus laevis.
1974,
Pubmed
,
Xenbase
Foulkes,
Steps in p-aminohippurate transport by kidney slices.
1959,
Pubmed
Frank,
The interaction between foreign and original motor nerves innervating the soleus muscle of rats.
1975,
Pubmed
Frank,
Interaction between foreign and original nerves innervating gill muscles in fish.
1976,
Pubmed
Gerencser,
Roles of sodium and potassium ions on p-aminohippurate transport in rabbit kidney slices.
1975,
Pubmed
Gerencser,
Sodium influence upon the transport kinetics of p-aminohippurate in rabbit kidney slices.
1973,
Pubmed
Grinnell,
Competitive interaction between foreign nerves innervating frog skeletal muscle.
1979,
Pubmed
HOFFMAN,
Local re-innervation in partially denervated muscle; a histophysiological study.
1950,
Pubmed
Kikuta,
Role of sodium ions in p-aminohippurate transport by newt kidney.
1979,
Pubmed
Koenig,
[Relation between the appearance of miniature end-plate potentials and the ultrastructure of reinnervating or newly formed end-plates in the rat].
1971,
Pubmed
Kuno,
Correlation between nerve terminal size and transmitter release at the neuromuscular junction of the frog.
1971,
Pubmed
Mark,
The mechanism of selective reinnervation of fish eye muscles. 3. Functional, electrophysiological and anatomical analysis of recovery from section of 3rd and IVth nerves.
1972,
Pubmed
Mark,
The mechanism of selective reinnervation of fish eye muscles. IV. Identification of repressed synapses.
1972,
Pubmed
Maxild,
Metabolic studies on renal transport of p-aminohippurate in vitro.
1969,
Pubmed
Maxild,
Energy requirements for active transport of p-aminohippurate in renal cortical slices.
1973,
Pubmed
Maxild,
Effect of externally added ATP and related compounds on active transport of p-aminohippurate and metabolism in cortical slices of the rabbit kidney.
1978,
Pubmed
Miyamoto,
Binomial analysis of quantal transmitter release at glycerol treated frog neuromuscular junctions.
1975,
Pubmed
MUDGE,
Electrolyte metabolism of rabbit-kidney slices; studies with radioactive potassium and sodium.
1953,
Pubmed
Okamoto,
Motor nerve terminals as the site of initial functional changes after denervation.
1969,
Pubmed
Podevin,
Concentrative PAH transport by rabbit kidney slices in the absence of metabolic energy.
1978,
Pubmed
Podevin,
Monovalent cation and ouabain effects on PAH uptake by rabbit kidney slices.
1977,
Pubmed
Rotshenker,
Synapse formation in intact innervated cutaneous-pectoris muscles of the frog following denervation of the opposite muscle.
1979,
Pubmed
Rotshenker,
Altered patterns of innervation in frog muscle after denervation.
1976,
Pubmed
Sanders,
Conduction velocity and myelin thickness in regenerating nerve fibres.
1946,
Pubmed
Scott,
Maintained function of foreign and appropriate junctions on reinnervated goldfish extraocular muscles.
1977,
Pubmed
Sheikh,
Characteristics of accumulation of probenecid by rabbit kidney cortical slices.
1977,
Pubmed
Sheikh,
The kinetic parameters of renal transport of p-aminohippurate in vitro.
1970,
Pubmed
SHIDEMAN,
Succinate oxidation and Krebs cycle as an energy source for renal tubular transport mechanisms.
1951,
Pubmed
Smith,
THE RENAL CLEARANCES OF SUBSTITUTED HIPPURIC ACID DERIVATIVES AND OTHER AROMATIC ACIDS IN DOG AND MAN.
1945,
Pubmed
Spencer,
Relationship between PAH transport and Na-K-ATPase activity in the rabbit kidney.
1979,
Pubmed
Tune,
Characteristics of p-aminohippurate transport in proximal renal tubules.
1969,
Pubmed
Weiner,
Effects of dinitrophenol and cyanide on TPAH and Na reabsorption.
1971,
Pubmed
Wernig,
Estimates of statistical release parameters from crayfish and frog neuromuscular junctions.
1975,
Pubmed
WHITTAM,
ION MOVEMENTS AND OXYGEN CONSUMPTION IN KIDNEY CORTEX SLICES.
1963,
Pubmed
WHITTAM,
Sodium and potassium movements in kidney cortex slices from new-born animals.
1960,
Pubmed
Woodhall,
Relationship between para-aminohippurate secretion and cellular morphology in rabbit proximal tubules.
1978,
Pubmed
