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Pseudouridine distribution in mammalian 18 S ribosomal RNA. A major cluster in the central region of the molecule.
Maden EH
,
Wakeman JA
.
Abstract
Human and rodent 18 S rRNA contain about 38 pseudouridine residues. By correlating RNA oligonucleotide data with complete sequence data derived from ribosomal DNA, 30 pseudouridine residues can be located in the RNA sequence, either exactly or to within two or three residues. Pseudouridine and 2'-O-methyl groups are interspersed throughout mammalian 18 S rRNA, but not in closely parallel fashion. Whereas the largest cluster of 2'-O-methyl groups is in the 5' one-third of the molecule, the greatest concentration of pseudouridine is in the central one-third of the molecule.
Amaldi,
Partial sequence analysis of ribosomal RNA from HeLa cells. I. Oligonucleotide pattern of 28 s and 18 s RNA after pancreatic ribonuclease digestion.
1968, Pubmed
Amaldi,
Partial sequence analysis of ribosomal RNA from HeLa cells. I. Oligonucleotide pattern of 28 s and 18 s RNA after pancreatic ribonuclease digestion.
1968,
Pubmed
Atmadja,
Xenopus laevis 18S ribosomal RNA: experimental determination of secondary structural elements, and locations of methyl groups in the secondary structure model.
1984,
Pubmed
,
Xenbase
Chan,
The nucleotide sequence of a rat 18 S ribosomal ribonucleic acid gene and a proposal for the secondary structure of 18 S ribosomal ribonucleic acid.
1984,
Pubmed
,
Xenbase
Choi,
Modified nucleotides in T1 RNase oligonucleotides of 18S ribosomal RNA of the Novikoff hepatoma.
1978,
Pubmed
Gonzalez,
The human 18S ribosomal RNA gene: evolution and stability.
1986,
Pubmed
Hughes,
The pseudouridine contents of the ribosomal ribonucleic acids of three vertebrate species. Numerical correspondence between pseudouridine residues and 2'-O-methyl groups is not always conserved.
1978,
Pubmed
,
Xenbase
Jeanteur,
Partial sequence analysis of ribosomal RNA from HeLa cells. II. Evidence for sequences of non-ribosmal type in 45 and 32 s ribosomal RNA precursors.
1968,
Pubmed
Khan,
Nucleotide sequences within the ribosomal ribonucleic acids of HeLa cells, Xenopus laevis and chick embryo fibroblasts.
1976,
Pubmed
,
Xenbase
Khan,
Extensive homologies between the methylated nucleotide sequences in several vertebrate ribosomal ribonucleic acids.
1978,
Pubmed
,
Xenbase
Maden,
The methylated nucleotide sequences in HELA cell ribosomal RNA and its precursors.
1974,
Pubmed
Maden,
Presence of a hypermodified nucleotide in HeLa cell 18 S and Saccharomyces carlsbergensis 17 S ribosomal RNAs.
1975,
Pubmed
Maden,
Standard and non standard products in combined T(1) plus pancreatic RNAase fingerprints of HeLa cell rRNA and its precursors.
1972,
Pubmed
Maden,
Clones of human ribosomal DNA containing the complete 18 S-rRNA and 28 S-rRNA genes. Characterization, a detailed map of the human ribosomal transcription unit and diversity among clones.
1987,
Pubmed
Maden,
Partial mapping of methylated sequences in Xenopus laevis ribosomal RNA by preparative hybridization to cloned fragments of ribosomal DNA.
1979,
Pubmed
,
Xenbase
Maden,
Identification of the locations of the methyl groups in 18 S ribosomal RNA from Xenopus laevis and man.
1986,
Pubmed
,
Xenbase
Maden,
Methylation map of Xenopus laevis ribosomal RNA.
1980,
Pubmed
,
Xenbase
Maden,
Methylated nucleotide sequences in HeLa-cell ribosomal ribonucleic acid. Correlation between the results from 'fingerprinting' hydrolysates obtained by digestion with T1 ribonuclease and with T1 plus pancreatic ribonuclease.
1977,
Pubmed
McCallum,
Human 18 S ribosomal RNA sequence inferred from DNA sequence. Variations in 18 S sequences and secondary modification patterns between vertebrates.
1985,
Pubmed
,
Xenbase
Nelles,
Nucleotide sequence of a crustacean 18S ribosomal RNA gene and secondary structure of eukaryotic small subunit ribosomal RNAs.
1984,
Pubmed
Raynal,
Complete nucleotide sequence of mouse 18 S rRNA gene: comparison with other available homologs.
1984,
Pubmed
,
Xenbase
Salim,
Nucleotide sequence encoding the 5' end of Xenopus laevis 18S rRNA.
1980,
Pubmed
,
Xenbase
Saponara,
The isolation from ribonucleic acid of substituted uridines containing alpha-aminobutyrate moieties derived from methionine.
1974,
Pubmed
Torczynski,
The complete nucleotide sequence of the rat 18S ribosomal RNA gene and comparison with the respective yeast and frog genes.
1983,
Pubmed
,
Xenbase
Torczynski,
Cloning and sequencing of a human 18S ribosomal RNA gene.
1985,
Pubmed
Vaughan,
The effects of methionine deprivation on ribosome synthesis in HeLa cells.
1967,
Pubmed
