Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.
XB-ART-26249
Biochimie 1990 Jan 01;721:65-72.
Show Gene links Show Anatomy links

Structural modifications induced by the mtDBP-C protein in the replication origin of Xenopus laevis mitochondrial DNA.

Mignotte B , Theveny B , Revet B .


Abstract
The structure of the non-coding region of Xenopus laevis mitochondrial DNA has been studied by electron microscopy analysis of DNA molecules end-labelled with streptavidin-ferritin. We have shown that the effect of a protein modifying the shape of the DNA double-helix can be studied and precisely located by this method. It was found that the non-coding region contains curved segments and that the mitochondrial protein mtDBP-C preferentially enhances the curvature of the promoters-replication origin region.

PubMed ID: 2111178