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Vitellogenin genes A1 and B1 are linked in the Xenopus laevis genome.
Wahli W
,
Germond JE
,
ten Heggeler B
,
May FE
.
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Genomic clones containing the Xenopus laevis vitellogenin gene B1 have been isolated from DNA libraries and characterized by heteroduplex mapping in the electron microscope, restriction endonuclease analysis, and in vitro transcription in a HeLa whole-cell extract. Sequences from the 3'-flanking region of the previously isolated A1 vitellogenin gene were found in the 5'-flanking region of this B1 gene. Thus, the two genes are linked, with 15.5 kilobase pairs of DNA between them. Their length is about 22 kilobase pairs (A1 gene) and 16.5 kilobase pairs (B1 gene) and they have the following arrangement: 5'-A1 gene-spacer-B1 gene-3'. The analysis of heteroduplexes formed between the two genes revealed several regions of homology. Both genes are in the same orientation and, therefore, are transcribed from the same DNA strand. The possible events by which the vitellogenin gene family arose in Xenopus laevis are discussed.
Bisbee,
Albumin phylogeny for clawed frogs (Xenopus).
1977, Pubmed,
Xenbase
Bisbee,
Albumin phylogeny for clawed frogs (Xenopus).
1977,
Pubmed
,
Xenbase
Dolan,
Chromosomal arrangement of the chicken beta-type globin genes.
1981,
Pubmed
Felber,
Isolation and translation in vitro of four related vitellogenin mRNAs of estrogen-stimulated Xenopus laevis.
1980,
Pubmed
,
Xenbase
Fritsch,
Molecular cloning and characterization of the human beta-like globin gene cluster.
1980,
Pubmed
Herrlich,
The endogenous proviral mouse mammary tumor virus genes of the GR mouse are not identical and only one corresponds to the exogenous virus.
1981,
Pubmed
Huber,
Thyroid hormone induces competence for oestrogen-dependent vitellogenin synthesis in developing Xenopus laevis liver.
1979,
Pubmed
,
Xenbase
Knowland,
Induction of vitellogenin synthesis in Xenopus laevis tadpoles.
1978,
Pubmed
,
Xenbase
Konkel,
The evolution and sequence comparison of two recently diverged mouse chromosomal beta--globin genes.
1979,
Pubmed
Maniatis,
The isolation of structural genes from libraries of eucaryotic DNA.
1978,
Pubmed
Manley,
DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract.
1980,
Pubmed
May,
Isolation and characterisation of the Xenopus laevis albumin genes: loss of 74K albumin gene sequences by library amplification.
1982,
Pubmed
,
Xenbase
McMaster,
Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.
1977,
Pubmed
Perrin,
The chicken conalbumin gene: studies of the organization of cloned DNAs.
1979,
Pubmed
Thiébaud,
DNA content in the genus Xenopus.
1977,
Pubmed
,
Xenbase
Ullrich,
Rat insulin genes: construction of plasmids containing the coding sequences.
1977,
Pubmed
Wahli,
Vitellogenin in Xenopus laevis is encoded in a small family of genes.
1979,
Pubmed
,
Xenbase
Wahli,
Isolation of two closely related vitellogenin genes, including their flanking regions, from a Xenopus laevis gene library.
1980,
Pubmed
,
Xenbase
Wahli,
Comparative analysis of the structural organization of two closely related vitellogenin genes in X. laevis.
1980,
Pubmed
,
Xenbase
Wahli,
Vitellogenesis and the vitellogenin gene family.
1981,
Pubmed
,
Xenbase
Westley,
Xenopus laevis serum albumins are encoded in two closely related genes.
1981,
Pubmed
,
Xenbase
Widmer,
Comparative analysis of cloned larval and adult globin cDNA sequences of Xenopus laevis.
1981,
Pubmed
,
Xenbase
