Tsitologiia 2008 Jan 01;505:394-405.

[Changes in Xenopus oocyte nucleus and cytoplasm organization after actin filaments depolymerization by latrunculin].

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Actin-containing filaments have been visualized inside the Xenopus oocyte nuclei due to combination of fluorescence and transmission electron microscopy. It has been shown that these filaments contact with nucleoli, spherical bodies and nuclear pore complexes. The incubation of oocytes with actin-depolymerizing latrunculin causes membrane vesiculation in the cytoplasm, and disruption of the nucleoplasm and nuclear envelope integrity. We suppose that actin-containing filaments belong to crucial cell components which are involved in coordination of nuclear-cytoplasmic interactions as well as distribution and transport of intranuclear components in growing Xenopus oocytes.

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Species referenced: Xenopus laevis
Genes referenced: actl6a