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XB-ART-27091
C R Acad Sci III 1989 Jan 01;3088:213-8.
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[Role of c-myc protein in the early embryonic development of Xenopus].

Méchali M , Evan G , Gusse M .


Abstract
Microinjections of antibodies directed against the protein encoded by the c-myc protooncogene strongly inhibit or arrest the early cell cleavage stage of Xenopus laevis embryos. Injections in one blastomere of a two cell stage embryo inhibit the segmentation of this blastomere. The cleavage of the uninjected blastomere behaves normally. Injections of control rabbit immunoglobulins do not alter the embryonic development.

PubMed ID: 2499407



Species referenced: Xenopus laevis
Genes referenced: myc