XB-ART-26824
J Biol Chem
1989 Apr 15;26411:6009-12.
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A protein-protein interaction is essential for stable complex formation on a 5 S RNA gene.
Abstract
Stable complex formation on a Xenopus somatic 5 S RNA gene requires protein-protein interactions between the non-DNA binding domain of transcription factor (TF) IIIA and activities in a TFIIIC fraction. No significant changes in the structure of the TFIIIA.DNA complex can be detected as a consequence of stabilization, indicating that protein confirmation is the primary determinant of stability.
PubMed ID: 2703476
Article link: J Biol Chem
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Species referenced: Xenopus laevis
Genes referenced: gtf3a gtf3c1