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XB-ART-28915
Comp Biochem Physiol C Comp Pharmacol Toxicol 1986 Jan 01;832:423-7. doi: 10.1016/0742-8413(86)90147-7.
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The influence of second messengers and related substances on the sensitivity of early embryos to cytostatic neurochemicals.

Shmukler YuB , Grigoriev NG , Buznikov GA , Turpaev TM .


Abstract
"Prenervous" neurotransmitters interact with second messengers in the regulation of early embryogenesis of sea urchins and the clawed frog Xenopus laevis. Propranolol and atropine inhibit cleavage divisions of X. laevis only after their intracellular administration. The level of the membrane potential (including a zero level) of the embryos studied is not essential for the cleavage divisions. Possible mechanisms of action of the "prenervous" neurotransmitters at the intracellular level and their coupling with second messengers are discussed.

PubMed ID: 2872009
Article link: Comp Biochem Physiol C Comp Pharmacol Toxicol