Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
Mol Cell Biol
1999 Jan 01;191:835-45. doi: 10.1128/MCB.19.1.835.
Show Gene links
Show Anatomy links
Two Xenopus proteins that bind the 3' end of histone mRNA: implications for translational control of histone synthesis during oogenesis.
Wang ZF
,
Ingledue TC
,
Dominski Z
,
Sanchez R
,
Marzluff WF
.
???displayArticle.abstract???
Translationally inactive histone mRNA is stored in frog oocytes, and translation is activated at oocyte maturation. The replication-dependent histone mRNAs are not polyadenylated and end in a conserved stem-loop structure. There are two proteins (SLBPs) which bind the 3' end of histone mRNA in frog oocytes. SLBP1 participates in pre-mRNA processing in the nucleus. SLBP2 is oocyte specific, is present in the cytoplasm, and does not support pre-mRNA processing in vivo or in vitro. The stored histone mRNA is bound to SLBP2. As oocytes mature, SLBP2 is degraded and a larger fraction of the histone mRNA is bound to SLBP1. The mechanism of activation of translation of histone mRNAs may involve exchange of SLBPs associated with the 3' end of histone mRNA.
Adamson,
Changes in the rate of histone synthesis during oocyte maturation and very early development of Xenopus laevis.
1977, Pubmed,
Xenbase
Adamson,
Changes in the rate of histone synthesis during oocyte maturation and very early development of Xenopus laevis.
1977,
Pubmed
,
Xenbase
Anderson,
Changing rates of histone mRNA synthesis and turnover in Drosophila embryos.
1980,
Pubmed
Ballantine,
Polyadenylation of histone mRNA in Xenopus oocytes and embryos.
1985,
Pubmed
,
Xenbase
Barkoff,
Meiotic maturation in Xenopus requires polyadenylation of multiple mRNAs.
1998,
Pubmed
,
Xenbase
Bouvet,
A role for transcription and FRGY2 in masking maternal mRNA within Xenopus oocytes.
1994,
Pubmed
,
Xenbase
Craig,
Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation.
1998,
Pubmed
Dominski,
The polyribosomal protein bound to the 3' end of histone mRNA can function in histone pre-mRNA processing.
1995,
Pubmed
Dumont,
Oogenesis in Xenopus laevis (Daudin). I. Stages of oocyte development in laboratory maintained animals.
1972,
Pubmed
,
Xenbase
Evans,
Biochemical fractionation of oocytes.
1991,
Pubmed
,
Xenbase
Fox,
Poly(A) removal during oocyte maturation: a default reaction selectively prevented by specific sequences in the 3' UTR of certain maternal mRNAs.
1990,
Pubmed
,
Xenbase
Fox,
Poly(A) addition during maturation of frog oocytes: distinct nuclear and cytoplasmic activities and regulation by the sequence UUUUUAU.
1989,
Pubmed
,
Xenbase
Gallie,
The histone 3'-terminal stem-loop is necessary for translation in Chinese hamster ovary cells.
1996,
Pubmed
Gebauer,
Translational control by cytoplasmic polyadenylation of c-mos mRNA is necessary for oocyte maturation in the mouse.
1994,
Pubmed
Hake,
Translational regulation of maternal mRNA.
1997,
Pubmed
,
Xenbase
Hanson,
Efficient extraction and partial purification of the polyribosome-associated stem-loop binding protein bound to the 3' end of histone mRNA.
1996,
Pubmed
Heasman,
Overexpression of cadherins and underexpression of beta-catenin inhibit dorsal mesoderm induction in early Xenopus embryos.
1994,
Pubmed
,
Xenbase
Kuge,
Cytoplasmic 3' poly(A) addition induces 5' cap ribose methylation: implications for translational control of maternal mRNA.
1995,
Pubmed
,
Xenbase
Levenson,
On the existence of polyadenylated histone mRNA in Xenopus laevis oocytes.
1976,
Pubmed
,
Xenbase
Li,
Transcription of the sea urchin U6 gene in vitro requires a TATA-like box, a proximal sequence element, and sea urchin USF, which binds an essential E box.
1994,
Pubmed
Martin,
The gene for histone RNA hairpin binding protein is located on human chromosome 4 and encodes a novel type of RNA binding protein.
1997,
Pubmed
Marzluff,
Histone 3' ends: essential and regulatory functions.
1992,
Pubmed
Matsumoto,
Translational repression dependent on the interaction of the Xenopus Y-box protein FRGY2 with mRNA. Role of the cold shock domain, tail domain, and selective RNA sequence recognition.
1996,
Pubmed
,
Xenbase
Matsumoto,
Nuclear history of a pre-mRNA determines the translational activity of cytoplasmic mRNA.
1998,
Pubmed
,
Xenbase
Maxson,
Expression and organization of histone genes.
1983,
Pubmed
,
Xenbase
Meric,
Regulated unmasking of in vivo synthesized maternal mRNA at oocyte maturation. A role for the chaperone nucleoplasmin.
1997,
Pubmed
,
Xenbase
Meric,
Masking and unmasking maternal mRNA. The role of polyadenylation, transcription, splicing, and nuclear history.
1996,
Pubmed
,
Xenbase
Munroe,
Tales of poly(A): a review.
1990,
Pubmed
Newport,
A major developmental transition in early Xenopus embryos: II. Control of the onset of transcription.
1982,
Pubmed
,
Xenbase
Perry,
Genomic organization and nucleotide sequence of two distinct histone gene clusters from Xenopus laevis. Identification of novel conserved upstream sequence elements.
1985,
Pubmed
,
Xenbase
Perry,
Major transitions in histone gene expression do not occur during development in Xenopus laevis.
1986,
Pubmed
,
Xenbase
Ruderman,
A portion of all major classes of histone messenger RNA in amphibian oocytes is polyadenylated.
1978,
Pubmed
Sallés,
Coordinate initiation of Drosophila development by regulated polyadenylation of maternal messenger RNAs.
1994,
Pubmed
SenGupta,
A three-hybrid system to detect RNA-protein interactions in vivo.
1996,
Pubmed
Sheets,
Polyadenylation of c-mos mRNA as a control point in Xenopus meiotic maturation.
1995,
Pubmed
,
Xenbase
Stebbins-Boaz,
CPEB controls the cytoplasmic polyadenylation of cyclin, Cdk2 and c-mos mRNAs and is necessary for oocyte maturation in Xenopus.
1996,
Pubmed
,
Xenbase
Sun,
The histone mRNA 3' end is required for localization of histone mRNA to polyribosomes.
1992,
Pubmed
Tarun,
Translation initiation factor eIF4G mediates in vitro poly(A) tail-dependent translation.
1997,
Pubmed
Tarun,
Association of the yeast poly(A) tail binding protein with translation initiation factor eIF-4G.
1996,
Pubmed
Van Dongen,
Histone gene expression in early development of Xenopus laevis. Analysis of histone mRNA in oocytes and embryos by blot-hybridization and cell-free translation.
1983,
Pubmed
,
Xenbase
Vassalli,
Regulated polyadenylation controls mRNA translation during meiotic maturation of mouse oocytes.
1989,
Pubmed
Verrotti,
Evolutionary conservation of sequence elements controlling cytoplasmic polyadenylylation.
1996,
Pubmed
,
Xenbase
Walker,
Unmasking mRNA in clam oocytes: role of phosphorylation of a 3' UTR masking element-binding protein at fertilization.
1996,
Pubmed
Wang,
The protein that binds the 3' end of histone mRNA: a novel RNA-binding protein required for histone pre-mRNA processing.
1996,
Pubmed
Wickens,
In the beginning is the end: regulation of poly(A) addition and removal during early development.
1990,
Pubmed
Williams,
Changes in the stem-loop at the 3' terminus of histone mRNA affects its nucleocytoplasmic transport and cytoplasmic regulation.
1994,
Pubmed
,
Xenbase
Williams,
The sequence of the stem and flanking sequences at the 3' end of histone mRNA are critical determinants for the binding of the stem-loop binding protein.
1995,
Pubmed
Woodland,
The synthesis and storage of histones during the oogenesis of Xenopus laevis.
1977,
Pubmed
,
Xenbase
Woodland,
Histone synthesis during the development of Xenopus.
1980,
Pubmed
,
Xenbase
