Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
Mamm Genome
1996 Mar 01;73:180-5. doi: 10.1007/s003359900050.
Show Gene links
Show Anatomy links
The porcine gene TBP10 encodes a protein homologous to the human tat-binding protein/26S protease subunit family.
Leeb T
,
Rettenberger G
,
Breech J
,
Hameister H
,
Brenig B
.
???displayArticle.abstract???
We have cloned a porcine gene, designated TBP1O, that belongs to the Tat-binding protein/26S protease subunit family. The genomic structure of the porcine TBP1O gene was analyzed after isolation of three overlapping genomic phage lambda clones. The TBP10 gene harbors 12 exons spanning 4.5 kb of chromosomal DNA. The TBP1O gene was assigned to Chromosome (Chr) 12 by fluorescence in situ hybridization (FISH) on metaphase chromosomes. The chromosomal location was confirmed by PCR analysis of a porcine-rodent hybrid cell panel. The TBP1O protein is encoded by a 1221 nucleotide cDNA and has a molecular mass of 45.6 kDa. The predicted amino acid sequence has highest similarity to the human and bovine p45 subunit of the 26S protease and the human transcription factor TRIP1. Further similarities were detected to the slime mold protein DdTBP1O and the Schizosaccharomyces pombe and Saccharomyces cerevisiae protein SUG1. Like DdTBP1O and other members of the protein family, the porcine TBP1O harbors a leucine zipper motif in the N-terminal region and a domain characteristics of ATP-dependent proteases in the C-terminal region.
Akiyama,
cDNA cloning of a new putative ATPase subunit p45 of the human 26S proteasome, a homolog of yeast transcriptional factor Sug1p.
1995, Pubmed
Akiyama,
cDNA cloning of a new putative ATPase subunit p45 of the human 26S proteasome, a homolog of yeast transcriptional factor Sug1p.
1995,
Pubmed
Cao,
Growth and developmental functions of a human immunodeficiency virus Tat-binding protein/26S protease subunit homolog from Dictyostelium discoideum.
1995,
Pubmed
Chevalet,
Statistical decision rules concerning synteny or independence between markers.
1986,
Pubmed
Confalonieri,
SAV, an archaebacterial gene with extensive homology to a family of highly conserved eukaryotic ATPases.
1994,
Pubmed
Coppieters,
Characterization of porcine polymorphic microsatellite loci.
1993,
Pubmed
DeMartino,
PA700, an ATP-dependent activator of the 20 S proteasome, is an ATPase containing multiple members of a nucleotide-binding protein family.
1994,
Pubmed
Dubiel,
Tat-binding protein 7 is a subunit of the 26S protease.
1994,
Pubmed
Dubiel,
Subunit 4 of the 26 S protease is a member of a novel eukaryotic ATPase family.
1992,
Pubmed
Dubiel,
Peptide sequencing identifies MSS1, a modulator of HIV Tat-mediated transactivation, as subunit 7 of the 26 S protease.
1993,
Pubmed
Ellegren,
Assignment of 20 microsatellite markers to the porcine linkage map.
1993,
Pubmed
Ellegren,
Abundant (A)n.(T)n mononucleotide repeats in the pig genome: linkage mapping of the porcine APOB, FSA, ALOX12, PEPN and RLN loci.
1993,
Pubmed
Erdmann,
PAS1, a yeast gene required for peroxisome biogenesis, encodes a member of a novel family of putative ATPases.
1991,
Pubmed
Fredholm,
Characterization of 24 porcine (dA-dC)n-(dT-dG)n microsatellites: genotyping of unrelated animals from four breeds and linkage studies.
1993,
Pubmed
Ghislain,
S. cerevisiae 26S protease mutants arrest cell division in G2/metaphase.
1993,
Pubmed
Gordon,
Defective mitosis due to a mutation in the gene for a fission yeast 26S protease subunit.
1993,
Pubmed
Gustavsson,
Standard karyotype of the domestic pig. Committee for the Standardized Karyotype of the Domestic Pig.
1988,
Pubmed
Hirtzlin,
Isolation of a novel Plasmodium falciparum gene encoding a protein homologous to the Tat-binding protein family.
1994,
Pubmed
Lee,
Interaction of thyroid-hormone receptor with a conserved transcriptional mediator.
1995,
Pubmed
Löwe,
Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution.
1995,
Pubmed
McQueen,
Anchorage of an unassigned linkage group to pig chromosome 10 with P1 clones.
1994,
Pubmed
Nelbock,
A cDNA for a protein that interacts with the human immunodeficiency virus Tat transactivator.
1990,
Pubmed
Ohana,
The type 1 human immunodeficiency virus Tat binding protein is a transcriptional activator belonging to an additional family of evolutionarily conserved genes.
1993,
Pubmed
Rettenberger,
Assignment of the Leydig insulin-like hormone to porcine chromosome 2q12-q13 by somatic cell hybrid analysis and fluorescence in situ hybridization.
1994,
Pubmed
Rettenberger,
Establishment of a partially informative porcine somatic cell hybrid panel and assignment of the loci for transition protein 2 (TNP2) and protamine 1 (PRM1) to chromosome 3 and polyubiquitin (UBC) to chromosome 14.
1994,
Pubmed
Rettenberger,
Chromosomal assignment of porcine microsatellites by use of a somatic cell hybrid mapping panel.
1994,
Pubmed
Rettenberger,
Chromosomal assignment of seventeen porcine microsatellites and genes by use of a somatic cell hybrid mapping panel.
1995,
Pubmed
Roth,
Gene assignment by means of somatic cell hybrids: a new method for the analysis of data.
1987,
Pubmed
Shaw,
Molecular cloning and developmental regulation of Dictyostelium discoideum homologues of the human and yeast HIV1 Tat-binding protein.
1993,
Pubmed
Shibuya,
New human gene encoding a positive modulator of HIV Tat-mediated transactivation.
1992,
Pubmed
Swaffield,
A highly conserved ATPase protein as a mediator between acidic activation domains and the TATA-binding protein.
1995,
Pubmed
