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Restriction mapping of the two proopiomelanocortin (POMC) genes of the South African clawed toad Xenopus laevis revealed that POMC gene A is much larger than POMCgene B. Here we report that this size difference is mainly due to the presence of four vitellogenin (Vi)-transposon-like elements in POMC gene A, while Vi elements are absent from POMCgene B. Alignment of these elements with other Vi elements revealed a consensus sequence of 463 bp, which is bounded by a 16 bp inverted repeat and flanked by a 3 bp direct repeat. Since the amounts of mRNA produced by both POMC genes in the pars intermedia of the Xenopus pituitary are similar, the presence of the Vi-transposon-like elements in POMC gene A apparently has no effect on POMC gene expression at transcriptional or post-transcriptional levels.
Bisbee,
Albumin phylogeny for clawed frogs (Xenopus).
1977, Pubmed,
Xenbase
Bisbee,
Albumin phylogeny for clawed frogs (Xenopus).
1977,
Pubmed
,
Xenbase
Georgiev,
Mobile genetic elements in animal cells and their biological significance.
1984,
Pubmed
Gerber-Huber,
Precursor-product relationship between vitellogenin and the yolk proteins as derived from the complete sequence of a Xenopus vitellogenin gene.
1987,
Pubmed
,
Xenbase
Hong,
A systemic DNA sequencing strategy.
1982,
Pubmed
Kuchler,
The genes for the frog skin peptides GLa, xenopsin, levitide and caerulein contain a homologous export exon encoding a signal sequence and part of an amphiphilic peptide.
1989,
Pubmed
,
Xenbase
Kuhn,
A 140-base-pair repetitive sequence element in the mouse rRNA gene spacer enhances transcription by RNA polymerase I in a cell-free system.
1990,
Pubmed
,
Xenbase
Lehrman,
Alu-Alu recombination deletes splice acceptor sites and produces secreted low density lipoprotein receptor in a subject with familial hypercholesterolemia.
1987,
Pubmed
Lin,
An improved DNA sequencing strategy.
1985,
Pubmed
Lowndes,
A short, highly repetitive element in intron -1 of the human c-Ha-ras gene acts as a block to transcriptional readthrough by a viral promoter.
1990,
Pubmed
Martens,
Expression of two proopiomelanocortin genes in the pituitary gland of Xenopus laevis: complete structures of the two preprohormones.
1986,
Pubmed
,
Xenbase
Martens,
Nucleotide sequence of cloned cDNA for pro-opiomelanocortin in the amphibian Xenopus laevis.
1985,
Pubmed
,
Xenbase
Meyerhof,
Sequence analysis of the upstream regions of Xenopus laevis beta-globin genes and arrangement of repetitive elements within the globin gene clusters.
1990,
Pubmed
,
Xenbase
Mohun,
Upstream sequences required for tissue-specific activation of the cardiac actin gene in Xenopus laevis embryos.
1986,
Pubmed
,
Xenbase
Sanger,
DNA sequencing with chain-terminating inhibitors.
1977,
Pubmed
Schubiger,
The Vi element. A transposon-like repeated DNA sequence interspersed in the vitellogenin locus of Xenopus laevis.
1985,
Pubmed
,
Xenbase
Thiébaud,
DNA content in the genus Xenopus.
1977,
Pubmed
,
Xenbase
van het Schip,
Conserved sequence motifs upstream from the co-ordinately expressed vitellogenin and apoVLDLII genes of chicken.
1986,
Pubmed
,
Xenbase
Wilbur,
Rapid similarity searches of nucleic acid and protein data banks.
1983,
Pubmed
Wu,
Negative regulation of the human epsilon-globin gene by transcriptional interference: role of an Alu repetitive element.
1990,
Pubmed
