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A processed gene potentially coding for a sarcomeric actin has been identified in Xenopus laevis and in the more primitive species X. tropicalis. The peptides encoded in these two species differ by two out of 377 amino acid residues. On the basis of the amino acid substitutions, the encoded peptide was identified as an alpha-skeletal actin in X. laevis and as an alpha-cardiac actin in X. tropicalis. Northern blot analysis and S1 mapping experiments suggest that in X. tropicalis the gene is expressed in embryos and adult heart. In X. laevis, transcripts homologous to this gene were found in embryos and in adult tissues, but predominantly in skeletal muscle rather than in heart.
Alonso,
Comparison of three actin-coding sequences in the mouse; evolutionary relationships between the actin genes of warm-blooded vertebrates.
1986, Pubmed
Alonso,
Comparison of three actin-coding sequences in the mouse; evolutionary relationships between the actin genes of warm-blooded vertebrates.
1986,
Pubmed
Andersen,
Rat metallothionein-1 structural gene and three pseudogenes, one of which contains 5'-regulatory sequences.
1986,
Pubmed
Bergsma,
Novel chicken actin gene: third cytoplasmic isoform.
1985,
Pubmed
Bisbee,
Albumin phylogeny for clawed frogs (Xenopus).
1977,
Pubmed
,
Xenbase
Breathnach,
Organization and expression of eucaryotic split genes coding for proteins.
1981,
Pubmed
Chang,
The complete sequence of the chicken alpha-cardiac actin gene: a highly conserved vertebrate gene.
1985,
Pubmed
Chien,
Isolation and characterization of calmodulin genes from Xenopus laevis.
1984,
Pubmed
,
Xenbase
Chirgwin,
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease.
1979,
Pubmed
Firtel,
Multigene families encoding actin and tubulin.
1981,
Pubmed
Fornwald,
The complete nucleotide sequence of the chick a-actin gene and its evolutionary relationship to the actin gene family.
1982,
Pubmed
Goff,
Structure of the Abelson murine leukemia virus genome and the homologous cellular gene: studies with cloned viral DNA.
1980,
Pubmed
Grichnik,
Tissue restricted and stage specific transcription is maintained within 411 nucleotides flanking the 5' end of the chicken alpha-skeletal actin gene.
1986,
Pubmed
Gunning,
Evolution of the human sarcomeric-actin genes: evidence for units of selection within the 3' untranslated regions of the mRNAs.
1984,
Pubmed
,
Xenbase
Gunning,
Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed.
1983,
Pubmed
Hu,
The complete sequence of the mouse skeletal alpha-actin gene reveals several conserved and inverted repeat sequences outside of the protein-coding region.
1986,
Pubmed
Jeffreys,
Linkage of adult alpha- and beta-globin genes in X. laevis and gene duplication by tetraploidization.
1980,
Pubmed
,
Xenbase
Khrestchatisky,
There is an alpha-actin skeletal muscle-specific gene in a salamander (Pleurodeles waltlii).
1987,
Pubmed
Leder,
Dispersion of alpha-like globin genes of the mouse to three different chromosomes.
,
Pubmed
Maxam,
Sequencing end-labeled DNA with base-specific chemical cleavages.
1980,
Pubmed
May,
Structure and evolution of the Xenopus laevis albumin genes.
1983,
Pubmed
,
Xenbase
McMaster,
Analysis of single- and double-stranded nucleic acids on polyacrylamide and agarose gels by using glyoxal and acridine orange.
1977,
Pubmed
Minty,
Number and organization of actin-related sequences in the mouse genome.
1983,
Pubmed
Minty,
A fetal skeletal muscle actin mRNA in the mouse and its identity with cardiac actin mRNA.
1982,
Pubmed
Minty,
Upstream regions of the human cardiac actin gene that modulate its transcription in muscle cells: presence of an evolutionarily conserved repeated motif.
1986,
Pubmed
Minty,
Two-level regulation of cardiac actin gene transcription: muscle-specific modulating factors can accumulate before gene activation.
1986,
Pubmed
Mohun,
Upstream sequences required for tissue-specific activation of the cardiac actin gene in Xenopus laevis embryos.
1986,
Pubmed
,
Xenbase
Mohun,
Cell type-specific activation of actin genes in the early amphibian embryo.
,
Pubmed
,
Xenbase
Moos,
Structure of a human beta-actin-related pseudogene which lacks intervening sequences.
1982,
Pubmed
Moos,
Structure of two human beta-actin-related processed genes one of which is located next to a simple repetitive sequence.
1983,
Pubmed
Ng,
Evolution of the functional human beta-actin gene and its multi-pseudogene family: conservation of noncoding regions and chromosomal dispersion of pseudogenes.
1985,
Pubmed
Nishioka,
Unusual alpha-globin-like gene that has cleanly lost both globin intervening sequences.
1980,
Pubmed
Perler,
The evolution of genes: the chicken preproinsulin gene.
1980,
Pubmed
Ponte,
Human actin genes are single copy for alpha-skeletal and alpha-cardiac actin but multicopy for beta- and gamma-cytoskeletal genes: 3' untranslated regions are isotype specific but are conserved in evolution.
1983,
Pubmed
Romans,
Organization of the actin multigene family of Dictyostelium discoideum and analysis of variability in the protein coding regions.
1985,
Pubmed
Sanger,
The use of thin acrylamide gels for DNA sequencing.
1978,
Pubmed
Spohr,
Organization and sequence analysis of a cluster of repetitive DNA elements from Xenopus laevis.
1981,
Pubmed
,
Xenbase
Stein,
Tissue-specific expression of a chicken calmodulin pseudogene lacking intervening sequences.
1983,
Pubmed
Stutz,
Isolation and characterization of sarcomeric actin genes expressed in Xenopus laevis embryos.
1986,
Pubmed
,
Xenbase
Sures,
Xenopsin: the neurotensin-like octapeptide from Xenopus skin at the carboxyl terminus of its precursor.
1984,
Pubmed
,
Xenbase
Sutoh,
Identification of myosin-binding sites on the actin sequence.
1982,
Pubmed
Thomas,
Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.
1980,
Pubmed
Tokunaga,
Structure of a processed gene of mouse cytoplasmic gamma-actin transposed into a BAM5 sequence: insertion has created 13 base-pair direct repeats.
1985,
Pubmed
Tymowska,
Chromosome complements of the genus Xenopus.
1973,
Pubmed
,
Xenbase
Vandekerckhove,
Chordate muscle actins differ distinctly from invertebrate muscle actins. The evolution of the different vertebrate muscle actins.
1984,
Pubmed
Vandekerckhove,
At least six different actins are expressed in a higher mammal: an analysis based on the amino acid sequence of the amino-terminal tryptic peptide.
1978,
Pubmed
Vandekerckhove,
The complete amino acid sequence of actins from bovine aorta, bovine heart, bovine fast skeletal muscle, and rabbit slow skeletal muscle. A protein-chemical analysis of muscle actin differentiation.
1979,
Pubmed
Vanin,
Processed pseudogenes. Characteristics and evolution.
1984,
Pubmed
Vanin,
A mouse alpha-globin-related pseudogene lacking intervening sequences.
1980,
Pubmed
Vogt,
Purification and further properties of single-strand-specific nuclease from Aspergillus oryzae.
1973,
Pubmed
Wahli,
Isolation of two closely related vitellogenin genes, including their flanking regions, from a Xenopus laevis gene library.
1980,
Pubmed
,
Xenbase
Zakut,
Nucleotide sequence of the rat skeletal muscle actin gene.
1982,
Pubmed