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Identification of Rauscher murine leukemia virus-specific mRNAs for the synthesis of gag- and env-gene products.
Zaane DV
,
Gielkens AL
,
Hesselink WG
,
Bloemers HP
.
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Polyadenylylated mRNA isolated from cells infected with Rauscher murine leukemia virus was fractionated by centrifugation in in a denaturing sucrose gradient into different sizes. Each RNA fraction was injected into oocytes of Xenopus laevis and the virus-specific products were analyzed by immunoprecipitation with polyvalent and monospecific antisera against polypeptides of Rauscher murine leukemia virus, and then by gel electrophoresis and scintillation autoradiography. It was shown that a 35S mRNA species directs the synthesis of a precursor of the internal or group-specific antigens of the virion (the gag-gene products). A 22S mRNA species directs the synthesis of two viral envelope polypeptides and their precursor polypeptide (env-gene products). The results indicate that the gag- and env-related polypeptides of Rauscher murine leukemia virus are synthesized uncoordinately and provide evidence for open and closed cistrons on the virus-specific mRNAs.
Aaronson,
Differential expression of helper viral structural polypeptides in cells transformed by clonal isolates of woolly monkey sarcoma virus.
1975, Pubmed
Aaronson,
Differential expression of helper viral structural polypeptides in cells transformed by clonal isolates of woolly monkey sarcoma virus.
1975,
Pubmed
Arcement,
Biosynthesis of Rauscher leukemia viral proteins: presence of p30 and envelope p15 sequences in precursor polypeptides.
1976,
Pubmed
Baltimore,
Tumor viruses: 1974.
1975,
Pubmed
Barbacid,
gag Gene of mammalian type-C RNA tumour viruses.
1976,
Pubmed
Bilello,
Murine sarcoma virus gene expression: transformants which express viral envelope glycoprotein in the absence of the major internal protein and infectious particles.
1974,
Pubmed
Bonner,
A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.
1974,
Pubmed
Butterworth,
Virus-specific proteins synthesized in encephalomyocarditis virus-infected HeLa cells.
1971,
Pubmed
Fan,
RNA metabolism of murine leukemia virus: detection of virus-specific RNA sequences in infected and uninfected cells and identification of virus-specific messenger RNA.
1973,
Pubmed
Gielkens,
Virus-specific messenger RNA on free and membrane-bound polyribosomes from cells infected with Rauscher leukemia virus.
1974,
Pubmed
Gielkens,
Synthesis of Rauscher murine leukemia virus-specific polypeptides in vitro.
1976,
Pubmed
Gurdon,
Use of frog eggs and oocytes for the study of messenger RNA and its translation in living cells.
1971,
Pubmed
,
Xenbase
Jacobson,
Polypeptide cleavages in the formation of poliovirus proteins.
1968,
Pubmed
Kerr,
Translation of murine leukemia virus RNA in cell-free systems from animal cells.
1976,
Pubmed
Molnar,
A proposed pathway of plasma glycoprotein synthesis.
1975,
Pubmed
Mueller-Lantzsch,
Monospecific immunoprecipitation of murine leukemia virus polyribosomes: identification of p30 protein-specific messenger RNA.
1976,
Pubmed
Naso,
A fucose-deficient glycoprotein precursor to Rauscher leukemia virus gp69/71.
1976,
Pubmed
Naso,
Biosynthesis of Rauscher leukemia viral proteins.
1975,
Pubmed
Salden,
Translation of Rauscher leukemia virus RNA in heterologous cell-free systems.
1976,
Pubmed
Salden,
Translation of Rauscher murine leukemia viral RNA. A model for the function of virus-specific messenger.
1976,
Pubmed
,
Xenbase
Salden,
Translation of oncogenic virus RNA in Xenopus laevis oocytes.
1976,
Pubmed
,
Xenbase
Salden,
Translation of avian myeloblastosis virus RNA in a reticulocyte cell-free system.
1976,
Pubmed
Schincariol,
Early synthesis of virus-specific RNA and DNA in cells rapidly transformed with Rous sarcoma virus.
1973,
Pubmed
Schochetman,
Independent polypeptide chain initiation sites for the synthesis of different classes of proteins for an RNA tumor virus: mouse mammary tumor virus.
1976,
Pubmed
Scolnick,
Isolation of temperature-sensitive mutants of murine sarcoma virus.
1972,
Pubmed
Shanmugam,
The virus-specific RNA species in free and membrane-bound polyribosomes of transformed cells replicating murine sarcoma-leukemia viruses.
1974,
Pubmed
Shapiro,
Proteolytic cleavage events in oncornavirus protein synthesis.
1976,
Pubmed
Shapiro,
High molecular weight precursor polypeptides to structural proteins of Rauscher murine leukemia virus.
1976,
Pubmed
Strand,
Structural proteins of ribonucleic acid tumor viruses. Purification of envelope, core, and internal components.
1976,
Pubmed
Van Zaane,
Virus-specific precursor polypeptides in cells infected with Rauscher leukemia virus: synthesis, identification, and processing.
1976,
Pubmed
von der Helm,
Translation of Rous sarcoma virus RNA in a cell-free system from ascites Krebs II cells.
1975,
Pubmed
Wang,
Distribution of envelope-specific and sarcoma-specific nucleotide sequences from different parents in the RNAs of avian tumor virus recombinants.
1976,
Pubmed
Zaanie,
Virus-specific precursor polypeptides in cells infected with Rauscher leukemia virus.
1975,
Pubmed
