Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
Proc Natl Acad Sci U S A
2007 Dec 26;10452:20944-8. doi: 10.1073/pnas.0710522105.
Show Gene links
Show Anatomy links
GABA(A)-current rundown of temporal lobe epilepsy is associated with repetitive activation of GABA(A) "phasic" receptors.
Palma E
,
Roseti C
,
Maiolino F
,
Fucile S
,
Martinello K
,
Mazzuferi M
,
Aronica E
,
Manfredi M
,
Esposito V
,
Cantore G
,
Miledi R
,
Simonato M
,
Eusebi F
.
Benarroch,
GABAA receptor heterogeneity, function, and implications for epilepsy.
2007, Pubmed
Benarroch,
GABAA receptor heterogeneity, function, and implications for epilepsy.
2007,
Pubmed
Draguhn,
Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+.
1990,
Pubmed
Dudek,
Zinc and Epileptogenesis.
2001,
Pubmed
Farrant,
Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors.
2005,
Pubmed
Frederickson,
Synaptically released zinc: physiological functions and pathological effects.
2001,
Pubmed
Gabriel,
Stimulus and potassium-induced epileptiform activity in the human dentate gyrus from patients with and without hippocampal sclerosis.
2004,
Pubmed
Korpi,
GABA(A) receptor subtypes as targets for neuropsychiatric drug development.
2006,
Pubmed
Lüscher,
Regulation of GABAA receptor trafficking, channel activity, and functional plasticity of inhibitory synapses.
2004,
Pubmed
Miledi,
Microtransplantation of neurotransmitter receptors from cells to Xenopus oocyte membranes: new procedure for ion channel studies.
2006,
Pubmed
,
Xenbase
Mortensen,
Extrasynaptic alphabeta subunit GABAA receptors on rat hippocampal pyramidal neurons.
2006,
Pubmed
Palma,
Expression of human epileptic temporal lobe neurotransmitter receptors in Xenopus oocytes: An innovative approach to study epilepsy.
2002,
Pubmed
,
Xenbase
Palma,
Abnormal GABAA receptors from the human epileptic hippocampal subiculum microtransplanted to Xenopus oocytes.
2005,
Pubmed
,
Xenbase
Palma,
The antiepileptic drug levetiracetam stabilizes the human epileptic GABAA receptors upon repetitive activation.
2007,
Pubmed
,
Xenbase
Palma,
BDNF modulates GABAA receptors microtransplanted from the human epileptic brain to Xenopus oocytes.
2005,
Pubmed
,
Xenbase
Palma,
Phosphatase inhibitors remove the run-down of gamma-aminobutyric acid type A receptors in the human epileptic brain.
2004,
Pubmed
,
Xenbase
Qi,
Downregulation of tonic GABA currents following epileptogenic stimulation of rat hippocampal cultures.
2006,
Pubmed
Racine,
Modification of seizure activity by electrical stimulation. II. Motor seizure.
1972,
Pubmed
Ragozzino,
Rundown of GABA type A receptors is a dysfunction associated with human drug-resistant mesial temporal lobe epilepsy.
2005,
Pubmed
,
Xenbase
Scimemi,
Tonic GABA(A) receptor-mediated currents in human brain.
2006,
Pubmed
Semyanov,
Tonically active GABA A receptors: modulating gain and maintaining the tone.
2004,
Pubmed
Sperk,
GABA and its receptors in epilepsy.
2004,
Pubmed
Stell,
Receptors with different affinities mediate phasic and tonic GABA(A) conductances in hippocampal neurons.
2002,
Pubmed
Stell,
Neuroactive steroids reduce neuronal excitability by selectively enhancing tonic inhibition mediated by delta subunit-containing GABAA receptors.
2003,
Pubmed
