Click here to close
Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly.
We suggest using a current version of Chrome,
FireFox, or Safari.
???displayArticle.abstract???
Some epithelia contain cells with multiple motile cilia that beat in a concerted manner. New tools and experimental systems have facilitated molecular studies of cilium biogenesis and the coordinated planar polarization of cilia that leads to their concerted motility. A recent elegant study using embryonic frog epidermis demonstrates that Dishevelled, a key regulator of both the Wnt-beta-catenin and planar cell polarity pathways, controls both the docking and planar polarization of ciliary basal bodies.
Boisvieux-Ulrich,
Determination of ciliary polarity precedes differentiation in the epithelial cells of quail oviduct.
1991, Pubmed
Boisvieux-Ulrich,
Determination of ciliary polarity precedes differentiation in the epithelial cells of quail oviduct.
1991,
Pubmed
Boisvieux-Ulrich,
The orientation of ciliary basal bodies in quail oviduct is related to the ciliary beating cycle commencement.
1985,
Pubmed
Boisvieux-Ulrich,
Cytochalasin D inhibits basal body migration and ciliary elongation in quail oviduct epithelium.
1990,
Pubmed
Classen,
Hexagonal packing of Drosophila wing epithelial cells by the planar cell polarity pathway.
2005,
Pubmed
Gomperts,
Foxj1 regulates basal body anchoring to the cytoskeleton of ciliated pulmonary epithelial cells.
2004,
Pubmed
Gromley,
Centriolin anchoring of exocyst and SNARE complexes at the midbody is required for secretory-vesicle-mediated abscission.
2005,
Pubmed
Habas,
Wnt/Frizzled activation of Rho regulates vertebrate gastrulation and requires a novel Formin homology protein Daam1.
2001,
Pubmed
,
Xenbase
Hagiwara,
Cell biology of normal and abnormal ciliogenesis in the ciliated epithelium.
2004,
Pubmed
Marshall,
The cell biological basis of ciliary disease.
2008,
Pubmed
Mitchell,
A positive feedback mechanism governs the polarity and motion of motile cilia.
2007,
Pubmed
,
Xenbase
Pan,
RhoA-mediated apical actin enrichment is required for ciliogenesis and promoted by Foxj1.
2007,
Pubmed
Park,
Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells.
2008,
Pubmed
,
Xenbase
Park,
Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling.
2006,
Pubmed
,
Xenbase
Qian,
Wnt5a functions in planar cell polarity regulation in mice.
2007,
Pubmed
,
Xenbase
Ross,
Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates.
2005,
Pubmed
Saburi,
Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease.
2008,
Pubmed
Seifert,
Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motility.
2007,
Pubmed
Shimada,
Polarized transport of Frizzled along the planar microtubule arrays in Drosophila wing epithelium.
2006,
Pubmed
Sorokin,
Centriole formation and ciliogenesis.
1968,
Pubmed
Vladar,
Molecular characterization of centriole assembly in ciliated epithelial cells.
2007,
Pubmed
Wu,
The ghost in the machine: small GTPases as spatial regulators of exocytosis.
2008,
Pubmed
Zallen,
Planar polarity and tissue morphogenesis.
2007,
Pubmed
