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XB-ART-4481
Opt Lett 2003 Nov 01;2821:2064-6. doi: 10.1364/ol.28.002064.
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High-resolution optical coherence microscopy for high-speed, in vivo cellular imaging.

Aguirre AD , Hsiung P , Ko TH , Hartl I , Fujimoto JG .


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Optical coherence microscopy (OCM) is demonstrated with a high-speed, broadband, reflective-grating phase modulator and a femtosecond Ti:Al2O3 laser. The novel system design permits high-resolution OCM imaging in a new operating regime in which a short coherence gate is used to relax the requirement for high-numerical-aperture confocal axial sectioning. In vivo cellular imaging is demonstrated in the Xenopus laevis tadpole and in human skin with a 3-microm coherence gate and a 30-microm confocal gate. The ability to achieve cellular imaging with a lower numerical aperture should facilitate the development of miniaturized probes for in vivo imaging applications.

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Genes referenced: ocm