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XB-ART-4699
FEBS Lett 2003 Sep 18;5521:12-6. doi: 10.1016/s0014-5793(03)00777-4.
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The viral potassium channel Kcv: structural and functional features.

Gazzarrini S , Severino M , Lombardi M , Morandi M , DiFrancesco D , Van Etten JL , Thiel G , Moroni A .


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The chlorella virus PBCV-1 was the first virus found to encode a functional potassium channel protein (Kcv). Kcv is small (94 aa) and basically consists of the M1-P-M2 (membrane-pore-membrane) module typical of the pore regions of all known potassium channels. Kcv forms functional channels in three heterologous systems. This brief review discusses the gating, permeability and modulation properties of Kcv and compares them to the properties of bacterial and mammalian K+ channels.

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