XB-ART-7582
Mol Cell
2002 Feb 01;92:213-24. doi: 10.1016/s1097-2765(02)00443-4.
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CtBP, an unconventional transcriptional corepressor in development and oncogenesis.
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CtBP family proteins are conserved among vertebrates and invertebrates and function as transcriptional corepressors. They repress transcription in a histone deacetylase-dependent or -independent manner. CtBPs play important roles during development and oncogenesis. In this review, their unusual properties, the mechanisms of transcriptional repression, regulation, and their biological functions are discussed.
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Species referenced: Xenopus laevis
Genes referenced: ctbp2