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XB-ART-24208
Dev Immunol 1992 Jan 01;24:295-307. doi: 10.1155/1992/41823.
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In vitro growth of thymic tumor cell lines from Xenopus.

Du Pasquier L , Robert J .


Abstract
A spontaneous lymphoid thymus tumor was discovered in a male Xenopus of the MHC ff genotype. The tumor cell can be transplanted in histocompatible larval ff hosts, but not in ff adults unless irradiated (3000 rad). The tumor is rejected by allogeneic hosts. The tumor cells express neither markers of the B-cell lineage nor MHC encoded molecules; they express only markers of the T-cell lineage. Its lymphoid population is clonal as revealed by the existence of a stable rearrangement pattern of the immunoglobulin genes. Cell lines growing continuously in vitro have been derived from the tumor.

PubMed ID: 1343098
PMC ID: PMC2275869
Article link: Dev Immunol


Species referenced: Xenopus
Genes referenced: mhc1a myh6
Antibodies: Cd8 Ab1 IgY Ab1 Leukocyte Ab2 Mhc1a Ab1 Mhc2a Ab1