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XB-ART-25534
Nucleic Acids Res 1990 Oct 11;1819:5811-6.
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HrpF, a human sequence-specific DNA-binding protein homologous to XrpFI, a Xenopus laevis oocyte transcription factor.

Lagna G , Loreni F , Beccari E , Carnevali F .


Abstract
The identification in HeLa nuclei of a novel DNA-binding protein, designated HrpF, is presented. This factor recognizes and binds a sequence of the Xenopus laevis L14 ribosomal protein (r-p) gene promoter bound by the Xenopus r-p transcription factor I (XrpFI). We show here that XrpFI and HrpF share a conserved DNA-binding domain. We also present evidences suggesting that the two factors perform similar functions in the cell. We discuss the hypothesis that closely related factors might be involved in the control of rp-gene transcription in vertebrates.

PubMed ID: 2216772
PMC ID: PMC332319
Article link: Nucleic Acids Res


Species referenced: Xenopus laevis
Genes referenced: gabpa

References [+] :
Atchison, Localization of transcriptional regulatory elements and nuclear factor binding sites in mouse ribosomal protein gene rpL32. 1989, Pubmed