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Brain Res Mol Brain Res 2003 Jul 23;1152:196-201. doi: 10.1016/s0169-328x(03)00173-6.
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Expression of 5-HT2B and 5-HT2C receptor genes is associated with proliferative regions of Xenopus developing brain and eye.

De Lucchini S , Ori M , Nardini M , Marracci S , Nardi I .

Here we clone the Xenopus 5-HT2B receptor cDNA and describe its spatio-temporal mRNA expression within the developing larval brain and visual system. Expression of the 5-HT2B transcripts is compared to that of 5-HT2C as well as proliferation and neurogenic markers. In developing brain and retina, 5-HT2B and 2C mRNAs are mainly expressed in proliferative regions. We suggest that these receptors may play a role in the larval secondary neurogenesis by mediating mitogenic effects of serotonin.

PubMed ID: 12877990
Article link: Brain Res Mol Brain Res

Species referenced: Xenopus
Genes referenced: ccnd1 htr2b htr2c notch1

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