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Gene 2002 Oct 30;3001-2:69-78.
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Molecular evolution of color vision in vertebrates.

Yokoyama S .

Visual systems of vertebrates exhibit a striking level of diversity, reflecting their adaptive responses to various color environments. The photosensitive molecules, visual pigments, can be synthesized in vitro and their absorption spectra can be determined. Comparing the amino acid sequences and absorption spectra of various visual pigments, we can identify amino acid changes that have modified the absorption spectra of visual pigments. These hypotheses can then be tested using the in vitro assay. This approach has been a powerful tool in elucidating not only the molecular bases of color vision, but the processes of adaptive evolution at the molecular level.

PubMed ID: 12468088

Grant support: [+]

Species referenced: Xenopus
Genes referenced: opn1lw opn1sw opn3 opn4 opn5 opn8 rho zswim7

Article Images: [+] show captions