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XB-ART-60277
MicroPubl Biol 2023 Jan 01;2023. doi: 10.17912/micropub.biology.000919.
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Expression and cilia associated localization of Histone deacetylases 6 in Xenopus.

Tisler M , Ott T , Blum M , Schweickert A .


Abstract
Histone deacetylases (HDACs) are key posttranslational modulators of the proteome. We show that expression of histone deacetylase 6 ( hdac6 ) is dynamic and appears in a tissue specific manner throughout embryonic development of the frog Xenopus laevis . Interestingly, hdac6 transcripts often associate with ciliated tissues, like the left-right organizer at neurula stage or the pronephros. In the embryonic skin, Hdac6 protein localizes to the cilia base, suggesting a functional link.

PubMed ID: 37649557
PMC ID: PMC10463039
Article link: MicroPubl Biol


Genes referenced: hdac6

References [+] :
Belo, Cerberus-like is a secreted factor with neutralizing activity expressed in the anterior primitive endoderm of the mouse gastrula. 1997, Pubmed, Xenbase