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Antibody Name: Fn1 Ab10 Common Name: 4B12 RRID: AB_2721945 Synonyms: cig, fibronectin, finc, FN, msf Antigens Gene: fn1 Clone Type: Monoclonal Source: Developmental Studies Hybridoma Bank

Antibody
Clone Number
Purification	Affinity Purification
Isotype	IgG1
Host Organism	mouse
Xenopus Reactivity	X. laevis
Non-Xenopus Reactivity
Description:	Fibronectin,epitope ,mapped to type III repeat 10. This antibody blocks cell attachment to fibronectin. Predicted (multiple isoforms):up to 270 kDa; Apparent: 220 kDa (multiple isoforms). 4B12 was deposited to the DSHB by DeSimone, D.W. CITE THIS: (DSHB Cat# 4B12, RRID:AB_2721945)
Immunogen
Name	fibronectin, type III repeat 10, function blocking
Type	polypeptide
Post Translational Modifications	None
Source Organism	frog
Description	Recombinant GST/FN (type III repeats 9 to 11) fusion protein, partial protein, Type III repeat 10
Sequence
Reported Usage
immunofluorescence
western blot	Predicted (multiple isoforms):up to 270 kDa; Apparent: 220 kDa (multiple isoforms)
Publications
???displayAntibody.papersFirst???	Integrin-dependent adhesive activity is spatially controlled by inductive signals at gastrulation., Development 1996
???displayAntibody.papersRecent???	Integrin alpha5beta1 function is regulated by XGIPC/kermit2 mediated endocytosis during Xenopus laevis gastrulation., PLoS One 2010
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