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XB-ANTIBODY-29208978
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Antibody Name:
H3-3a Ab43
Common Name: H3K27me3 RRID: AB_2943245 Synonyms: Tri-Methyl-Histone H3 (Lys27)
Source: Cell Signaling Technology |
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| Antibody | |
| Clone Number | C36B11 |
| Purification | |
| Isotype | IgG |
| Host Organism | rabbit |
| Xenopus Reactivity | X. laevis |
| Non-Xenopus Reactivity | human, monkey, mouse, rat |
| Description: | Tri-Methyl-Histone H3 (Lys27) (C36B11) Rabbit mAb detects endogenous levels of histone H3 only when tri-methylated on Lys27. The antibody does not cross-react with non-methylated, mono-methylated or di-methylated Lys27. In addition, the antibody does not cross-react with mono-methylated, di-methylated or tri-methylated histone H3 at Lys4, Lys9, Lys36 or Histone H4 at Lys20. |
| Immunogen | |
| Name | h3-3a K27me3 |
| Type | synthetic sequence |
| Post Translational Modifications | Methylated |
| Source Organism | Other |
| Description | Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the amino terminus of histone H3 in which Lys27 is tri-methylated. |
| Sequence | |
| Reported Usage | |
| chromatin immunoprecipitation | |
| Publications | |
| ???displayAntibody.papersFirst??? |
BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers., Sci Adv 2019 |
| ???displayAntibody.papersRecent??? | |
| ???displayAntibody.papersAll??? | |
