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Antibody Name: Kif5b Ab1

Common Name: Kinesin 1

RRID: AB_528326
Synonyms: kinesin heavy chain, head region, SUK 4


Clone Type: Monoclonal

Clone Number SUK 4
Isotype IgG1
Host Organism mouse
Xenopus Reactivity
Non-Xenopus Reactivity
Description: Inhibits sea urchin egg kinesin-induced microtubule translocation. Head region of kinesin heavy chain containing the microtubule-binding region.. SUK 4 doesn't cross react with squid kinesin. In mice, SUK 4 recognizes the three kinesin-1 KIF5A, KIF5B and KIF5C, with a more intense stainning for KIF5A Citation:(DSHB Cat# SUK 4, RRID:AB_528326). and PMID:2974459
Name Kinesin 1
Type polypeptide
Post Translational Modifications None
Source Organism Other
Description Raised against Full length protein of sea urchin kinesin-1. The epitope is located on aa 336-390 of the Drosophila kinesin heavy chain which corresponds to aa 328-382 of the urchin protein.
Reported Usage
immunohistochemistry 1:250
immunoprecipitation Actually immuno-inhibition/suppression
western blot
Used For Epitope Tagging Yes
First: Inhibition of kinesin-driven microtubule motility by monoclonal antibodies to kinesin heavy chains., J Cell Biol 1988  
Most recent: Kinesin-1 heavy chain mediates microtubule sliding to drive changes in cell shape., Proc Natl Acad Sci U S A 2010  
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