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XB-ANTIBODY-14579962
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Antibody Name:
Cdh1 Ab2
Common Name: E-cadherin RRID: AB_528117 Synonyms: 8C2, cd324, cdhe, ecad
Source: Developmental Studies Hybridoma Bank |
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| Antibody | |
| Clone Number | 8C2 |
| Purification | |
| Isotype | IgG1 |
| Host Organism | mouse |
| Xenopus Reactivity | X. tropicalis, X. laevis |
| Non-Xenopus Reactivity | chicken |
| Description: | Generated by Barry Gumbiner. Supplied by DSHB, Cat# 8C2c Citation: (DSHB Cat# 8c2, RRID:AB_528117). Please email citation to DSHB. |
| Immunogen | |
| Name | E-cadherin |
| Type | polypeptide |
| Post Translational Modifications | None |
| Source Organism | frog |
| Description | Purified E-cadherin extracellular domain (100 kDa trypsin fragment ectodomain) from Xenopus A6 kidney cell line. 8C2 only binds the -(Ca++) conformation of E-cadherin. Blocks epithelial cell-cell adhesion and cell junction formation. Stains ectoderm, all epithelia and regions of cell-cell contact. E-cadherin-specific by immunoblotting and immunoprecipitation. |
| Sequence | |
| Reported Usage | |
| western blot | |
| immunoprecipitation | |
| immunofluorescence | |
| Publications | |
| First: |
Expression of cell adhesion molecule E-cadherin in Xenopus embryos begins at gastrulation and predominates in the ectoderm., J Cell Biol 1989 |
| Most recent: |
Interaction between SPARC and tubulin in Xenopus., Cell Tissue Res 2004 |
| View All Papers | |