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Antibody Name: Stx1a Ab1 Common Name: munc18-1 RRID: Synonyms: syntaxin Antigens Gene: stx1a , syt1 XAO: retina, brain Clone Type: Monoclonal Source: Sigma-Aldrich

Antibody
Clone Number	HPC-1
Purification	Ascites
Isotype	IgG1
Host Organism	mouse
Xenopus Reactivity	X. tropicalis, X. laevis
Non-Xenopus Reactivity	cow, rabbit, rat
Description:	Syntaxin is a 35kD synaptic protein capable of interacting with the synaptic vesicle protein synaptotagmin. It facilitates the docking and fusion of synaptic vesicles with the plasma membrane. Monoclonal anti-syntaxin antibody can be used to screen lamda gt 11 library of rat hippocampus to isolate syntaxin cDNA clones. It can also be used in microarray and immunocytochemistry. Mouse anti-syntaxin antibody reacts specifically with membrane protein syntaxin (35 kD). Not yet shown to work in Xenopus.
Immunogen
Name
Type	homogenized tissue
Post Translational Modifications	None
Source Organism	Other
Description	synaptosomal plasma-membrane fraction from adult rat hippocampus.
Sequence
Reported Usage
western blot	1:1000 dilution
Publications
First:	Distinct domain-dependent effect of syntaxin1A on amiloride-sensitive sodium channel (ENaC) currents in HT-29 colonic epithelial cells., Int J Biol Sci 2006
Most recent:
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