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XB-ANTIBODY-23622743

Antibody Name: Fn1 Ab10

Common Name: 4B12

RRID: AB_2721945
Synonyms: FN, cig, fibronectin, finc, msf

Antigens
Gene: fn1

Clone Type: Monoclonal
Source: Developmental Studies Hybridoma Bank

Antibody
Clone Number
Purification Affinity Purification
Isotype IgG1
Host Organism mouse
Xenopus Reactivity X. laevis
Non-Xenopus Reactivity
Description: Fibronectin,epitope ,mapped to type III repeat 10. This antibody blocks cell attachment to fibronectin. Predicted (multiple isoforms):up to 270 kDa; Apparent: 220 kDa (multiple isoforms). 4B12 was deposited to the DSHB by DeSimone, D.W. CITE THIS: (DSHB Cat# 4B12, RRID:AB_2721945)
Immunogen
Name fn1
Type polypeptide
Post Translational Modifications None
Source Organism frog
Description Recombinant GST/FN (type III repeats 9 to 11) fusion protein.
Sequence
Reported Usage
immunofluorescence
western blot
Publications
First: Integrin-dependent adhesive activity is spatially controlled by inductive signals at gastrulation., Development 1996  
Most recent: Integrin alpha5beta1 function is regulated by XGIPC/kermit2 mediated endocytosis during Xenopus laevis gastrulation., PLoS One 2010                        
View All Papers