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XB-ANTIBODY-25874711

Antibody Name: Mapk1/3 Ab20

Common Name: Phospho-p44/42 MAPK

RRID: AB_331775
Synonyms: 4377s, 4377t, erk1/2

Antigens

Clone Type: Monoclonal
Source: Cell Signaling Technology

Antibody
Clone Number
Purification Affinity Purification
Isotype IgG
Host Organism rabbit
Xenopus Reactivity X. tropicalis, X. laevis
Non-Xenopus Reactivity fruitfly, human, monkey, mouse, pig, rat, zebrafish
Description: Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs, such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines (1-3), and research investigators consider it an important target in the diagnosis and treatment of cancer
Immunogen
Name mapk
Type synthetic sequence
Post Translational Modifications Phosphorylated
Source Organism human
Description Monoclonal antibody is produced by immunizing animals with a synthetic phosphopeptide corresponding to residues surrounding Thr202/Tyr204 of human p44 MAP kinase.
Sequence
Reported Usage
western blot 1:1000
immunofluorescence 1:200
flow cytometry 1:200-1:800
Publications
First: Injury-induced Erk1/2 signaling tissue-specifically interacts with Ca2+ activity and is necessary for regeneration of spinal cord and skeletal muscle., Cell Calcium 2022                                    
Most recent:
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